Evidence map›Paper›PMID 40538508›Full record

ArticleWorld journal of gastroenterology2025

Microbiota geography in the colorectal carcinoma microenvironment: A spatiotemporal atlas of colonic mucosal microbial niche reconstruction.

Zong-Qiang Han, Li-Na Wen

Abstract readLetter
In one paragraph

Article in World journal of gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zong-Qiang HanDepartment of Laboratory Medicine, Beijing Xiaotangshan Hospital, Beijing 102211, China.
Li-Na WenDepartment of Clinical Nutrition, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China. wenlina3074@bjsjth.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A case-control study on the differences in colonic mucosa-associated microbiotas between patients with and without colorectal cancer (CRC) in the Indonesian population was recently published. The geographical distribution characteristics of the gut microbiota in the carcinogenic microenvironment are closely related to disease progression. Therefore, the results of that study are of great significance for determining the pathogenesis of CRC in the Indonesian region and for clinically diagnosing and treating CRC. While acknowledging the strengths of the study, its limitations should also be addressed. Future case-control studies of the gut microbiota based on specific populations should be further refined to provide more optimized guidance for clinical precision treatment.

Indexed as

ColonColorectal NeoplasmsGastrointestinal MicrobiomeIntestinal MucosaTumor MicroenvironmentCase-Control StudiesDisease ProgressionHumansIndonesiaSpatio-Temporal AnalysisCase control studyColon mucosaColorectal cancerGeographyMicrobiota

Identifiers

PMID40538508
PMCPMC12175864

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.