ArticleSleep and biological rhythms2025
Association between sleep disorders and osteoporosis in the elderly at high altitude in China.
Article in Sleep and biological rhythms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sleep disorders and osteoporosis frequently co-occur in the elderly, especially among those living at high altitudes. This study aimed to investigate the association between sleep disorders and osteoporosis among elderly residents of high-altitude regions in China. We conducted a cross-sectional analysis from January 2021 to January 2023, enrolling 160 elderly participants aged 60 years and older from high-altitude areas. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI), and osteoporosis was diagnosed using dual-energy X-ray absorptiometry (DEXA). Demographic data, blood parameters, and pulmonary artery pressure were collected. Statistical analyses included descriptive statistics, correlation analysis, and logistic regression to determine the independent association between sleep disorders and osteoporosis, adjusting for potential confounders. Osteoporosis was prevalent in 65% of the participants, with 75% of those also having sleep disorders. A significant negative correlation was found between sleep quality and bone density (ρ = -0.65, P < 0.001), suggesting a positive relationship between the severity of sleep disorders and the risk of osteoporosis. Multivariate logistic regression analysis revealed a significant association between sleep disorders and the presence of osteoporosis (OR = 1.67, 95% CI: 1.20-2.20, P = 0.001). Subgroup analyses showed stronger associations in females (OR = 2.20, 95% CI: 1.50-3.20, P < 0.001) and participants aged over 70 years (OR = 2.00, 95% CI: 1.30-3.10, P = 0.002). Significant correlations were also observed in participants with oxygen saturation below 85% (OR = 2.50, 95% CI: 1.60-3.90, P < 0.001) and those with elevated pulmonary artery pressure (OR = 2.80, 95% CI: 1.80-4.30, P < 0.001). Sleep disorders are significantly associated with osteoporosis in the elderly at high altitudes, with physiological variables in this environment potentially exacerbating this relationship.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.