Evidence map›Paper›PMID 40538380›Full record

ArticleJournal of multidisciplinary healthcare2025

Chronic Lung Diseases and Depressive Symptoms in Older Adults: Insights from Observational Studies and Mendelian Randomization.

Huifang Liu, Yisong Yao, Yujuan Yang, Jianwei Wang, Jingyi Yu, Xinjun Xu, Xianghuang Luo, Yu Zhang, Xicheng Song

Abstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huifang Liu *Second Clinical Medicine College, Binzhou Medical University, Yantai, People's Republic of China.
Yisong Yao *Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Yujuan Yang *Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Jianwei WangDepartment of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Jingyi YuDepartment of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Xinjun XuDepartment of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Xianghuang LuoDepartment of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Yu ZhangDepartment of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.
Xicheng SongDepartment of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, People's Republic of China.ORCID 0000-0002-9789-1318

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: To elucidate the currently unknown relationship between chronic lung diseases (CLDs) and depressive symptoms among older adults. Methods: A total of 8079 older adults from China Longitudinal Aging Social Survey (CLASS) and 1119 individuals from a Sichuan Province cohort were included in this study. We used regression analysis and propensity score matching (PSM) to assess the association between CLDs and depressive symptoms among older adults, while the causal relationship was assessed using Mendelian randomization (MR). Our sensitivity analyses included heterogeneity tests, tests of multiple validity, and leave-one-out tests. A two-way mediation analysis was also used to assess the mediating role of basic activities of daily living (BADL) between CLDs and depressive symptoms. Results: In this cross-sectional study, we found that depressive symptoms significantly ( Conclusion: Depressive symptoms are associated with an increased risk of CLDs, reduced BADL promote the risk of CLDs in older adults with depressive symptoms, but the underlying pathological mechanism still needs to be clarified in future research.

Indexed as

chronic lung diseasescross-sectional studydepressive symptomsMendelian randomizationpropensity score matching

Identifiers

PMID40538380
PMCPMC12178258

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.