Evidence map›Paper›PMID 40538167›Full record

ReviewRenal failure2025

Multi-target regulation of cellular senescence by traditional Chinese medicine: a novel strategy to preventing diabetic kidney disease.

Chen Wang, Dongfeng Chen, Yonghui Yin, Xiujuan Liu, Yi Liu, Xiaoyun Li, Chang Kong, Quanlin Zhao

Abstract readReview
In one paragraph

Review in Renal failure, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chen WangThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Dongfeng ChenThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Yonghui YinAffiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Xiujuan LiuThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Yi LiuThe First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Xiaoyun LiSchool of Nursing, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Chang KongSchool of Nursing, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
Quanlin ZhaoAffiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic kidney disease (DKD) is a common chronic microvascular complication of diabetes and the leading cause of end-stage renal disease. Its pathogenesis is closely linked to cellular senescence. Studies have shown that cellular senescence drives DKD progression

Indexed as

Cellular SenescenceDiabetic NephropathiesDrugs, Chinese HerbalMedicine, Chinese TraditionalAMP-Activated Protein KinasesHumansOxidative StressSignal TransductionTOR Serine-Threonine KinasesAMP-Activated Protein KinasesDrugs, Chinese HerbalTOR Serine-Threonine Kinasescellular senescenceDiabetic kidney diseasemechanism studytraditional chinese medicine

Identifiers

PMID40538167
PMCPMC12893495

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.