ArticleJournal of cosmetic dermatology2025
Clinical Analysis of PRP Combined With Hyaluronic Acid Mesotherapy in the Treatment of Facial Chloasma.
Article in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Regenerative Skin Remodeling by a Dual Hyaluronic Acid Hybrid Complex in Multimodal Preclinical Models.International journal of molecular sciences · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo study the safety and clinical effect of PRP combined with hyaluronic acid (HA) mesotherapy in the treatment of facial chloasma, to explore a safe and effective treatment option for chloasma.
methods57 patients with chloasma who received mesotherapy were analyzed in this study. They were divided into 19 cases of the PRP combined with HA mesotherapy group (PRP+HA group), 20 cases of the PRP mesotherapy group (PRP group) and 18 cases of the hyaluronic acid mesotherapy group (HA group). The therapeutic effect of chloasma was evaluated at the fourth week after treatment, including the decrease rate of chloasma area and severity index (MASI), the effective rate, the decrease rate of pigment degree, the decrease rate of pigment area, and the decrease rate of pigment quantity. The patient's satisfaction and adverse reactions were investigated. The safety and efficacy of each group were compared and analyzed.
resultsThe effective rate of chloasma treatment in the PRP group and the PRP+HA group was more than 50% at 4 weeks after treatment. The improvement of the above indexes in the PRP+HA group was better than those in the single treatment group. The satisfaction of the PRP+HA group was higher than that of the HA group, and the satisfaction of the other groups was not significantly different. There were no serious adverse reactions in the three groups.
conclusionPRP mesotherapy alone or combined with HA and PRP mesotherapy can effectively treat chloasma, and the combined treatment effect is better, which is worthy of clinical promotion.
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