ArticleMagnetic resonance in chemistry : MRC2025
NMR Relaxometry Across Time: From Early Insights to Emerging Directions.
Article in Magnetic resonance in chemistry : MRC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Pilot Study on the Use of Low-Field Nuclear Magnetic Resonance as a Noninvasive Tool for Monitoring Mucus in Obstructive Lung Diseases.International journal of molecular sciences · 2026Article
- Dose-Dependent Effects of Biochar on Soil Revealed by Fast Field-Cycling (FFC) NMR: From Molecular Water Dynamics to Soil Functionality.Magnetic resonance in chemistry : MRC · 2026Article
- NMR-Based Quantification of Collagen Content in Protein Hydrolysates.Journal of agricultural and food chemistry · 2026Article
- NMR Relaxometry Across Time: From Early Insights to Emerging Directions.Magnetic resonance in chemistry : MRC · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nuclear magnetic resonance (NMR) relaxometry has evolved from early theoretical insights into a dynamic and versatile analytical technique capable of probing molecular and ionic motion across diverse fields. Rooted in the foundational work by many different scientists (e.g., Bloch, Purcell, Torrey, Hahn, Bloembergen, Pound, and Solomon, just to name a few), relaxometry has progressed through pivotal advancements such as Redfield's theory and the development of time-domain (TD) and fast field-cycling (FFC) methodologies. While the former enables rapid, low-cost analysis of relaxation time distributions, widely applied in soft matter and quality control, the latter provides frequency-resolved nuclear magnetic resonance dispersion (NMRD) profiles that capture dynamic processes across multiple timescales, revealing deeper insights into molecular interactions in heterogeneous systems. Recent innovations in instrumentation have expanded the applicability of relaxometry. Moreover, its integration with modalities such as diffusimetry and imaging has opened new routes for spatially resolved and multimodal analyses. Applications now span materials science, biomedicine, and environmental studies. In polymers and porous media, relaxometry reveals segmental dynamics and surface interactions; in biological tissues, NMRD profiles differentiate healthy from pathological states, offering diagnostic potential. Emerging applications include contrast agent development, soil hydration analysis, microplastic detection, and wastewater monitoring. This paper offers a comprehensive overview of the field's historical trajectory, methodological advancements, and expanding application landscape. Emphasis is placed on the synergy between TD and FFC-NMR approaches and the ongoing transition toward portable, real-time, and multimodal relaxometric systems. NMR relaxometry is poised to become a mainstream tool in diagnostics, materials characterization, and environmental monitoring.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.