Evidence map›Paper›PMID 40537858›Full record

ArticleEuropean journal of medical research2025

Gait variability and biomechanical distinctions in individuals with functional ankle instability: a case-control study based on three-dimensional motion analysis.

Dunbing Huang, Chen Zhang, Wei Song, Jiaxin Gao, Huan Tian, Huaqiang Li, Xiaohua Ke, Cai Jiang, Zhonghua Lin

Abstract read
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Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dunbing Huang *Encephalopathy and Rehabilitation Center, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310005, Zhejiang, China.
Chen Zhang *Department of Rehabilitation Medicine, The Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, 310005, Zhejiang, China.
Wei Song *Department of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, 1279 Sanmen Road, Hongkou District, Shanghai, 200434, China.
Jiaxin GaoDepartment of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, 1279 Sanmen Road, Hongkou District, Shanghai, 200434, China.
Huan TianDepartment of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, 1279 Sanmen Road, Hongkou District, Shanghai, 200434, China.
Huaqiang LiDepartment of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, 1279 Sanmen Road, Hongkou District, Shanghai, 200434, China.
Xiaohua KeDepartment of Rehabilitation Medicine, Shanghai Fourth People's Hospital, School of Medicine, Tongji University, 1279 Sanmen Road, Hongkou District, Shanghai, 200434, China. kxh22@tongji.edu.cn.
Cai JiangShengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. jiangcai88@126.com.
Zhonghua LinShengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China. doctor_lzh71@163.com.

Funding

Fujian Science and Technology Department 2023Y0052National Natural Science Foundation of China 81904271Natural Science Foundation of Fujian Province 2020J05268
6 · The paper itself

Abstract

backgroundAnkle sprains, the most common sports injury, often progress to functional ankle instability (FAI), characterized by recurrent instability and neuromuscular deficits. This study utilizes three-dimensional (3D) gait analysis system to quantify lower limb biomechanical alterations in FAI during gait, aiming to identify objective markers for guiding targeted rehabilitation strategies. STUDY

designThis case-control study enrolled 31 matched subject pairs (FAI subjects vs. healthy controls) through propensity score matching based on stringent inclusion/exclusion criteria. Demographic data were collected, and functional assessments including the Cumberland Ankle Instability Tool (CAIT), American Orthopedic Foot and Ankle Society (AOFAS) scale, and Visual Analog Scale (VAS) for pain were administered. 3D gait analysis was performed using an infrared motion capture system (BTS SMART-D 400) to quantify biomechanical parameters characterizing FAI-related gait abnormalities.

resultsIn individuals with FAI gait quality is significantly compromised, predominantly evidenced by alterations in pelvic tilt (P < 0.05, r = - 0.67, 95% CI [- 4.75, - 1.95]), as well as deviations in hip ad-abduction (P < 0.05, r = 0.44, 95% CI [- 3.80, - 0.20]). This condition is further characterized by a marked reduction in sagittal plane flexion of the hip joint (P < 0.05, r = - 0.44, 95% CI [0.60, 8.25]) and a decrease in the maximum dorsiflexion of the ankle joint (P < 0.05, r = - 2.56, 95% CI [- 3.76, 0.50]). Additionally, there is an observed increase in the dorsiflexion angle at the forefoot (P < 0.05, r = - 11.04, 95% CI [1.36,4.94]), coupled with a decrease in the dorsiflexion angle at the hindfoot (P < 0.05, r = - 13.16, 95% CI [0.25,4.10]).

conclusionsPost-traumatic degradation of peripheral sensorimotor feedback following ankle injury induces central nervous system-mediated motor control reorganization, resulting in altered movement strategies that manifest through modified kinematic coordination patterns across the hip, knee, and ankle joints.

Indexed as

Ankle InjuriesAnkle JointGaitJoint InstabilityAdultBiomechanical PhenomenaCase-Control StudiesFemaleGait AnalysisHumansMaleYoung AdultCompensatory mechanismsKinematic alterationsPostural stabilityRehabilitation strategiesSensorimotor deficits

Identifiers

PMID40537858
PMCPMC12178026

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.