ArticleArthritis research & therapy2025
Global burden and trends of musculoskeletal disorders in postmenopausal elderly women: a 1990-2021 analysis with projections to 2045.
Article in Arthritis research & therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Chondrogenic niche hydrogel microspheres facilitate cartilage regeneration in osteoarthritis.Bioactive materials · 2026Article
- Sex-specific burden of osteoarthritis and rheumatoid arthritis across Asia, 1990-2023: a Global Burden of Disease Study 2023.Clinical rheumatology · 2026Article
- Global Epidemiology of Amputation-Related Disability From 1990 to 2021: Geographic Variation and Projections to 2050.Journal of cachexia, sarcopenia and muscle · 2026Article
- Global, regional and national burden of osteoarthritis in women of childbearing age from 1990 to 2021, with projected trends up to 2045.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Radiographic knee osteoarthritis is associated with higher lumbar spine bone mineral density but not reduced vertebral fracture prevalence: a retrospective cross-sectional study in older Asian women.BMC musculoskeletal disorders · 2026Article
- Emerging concepts in osteoarthritis and musculoskeletal diseases: Insights from the University of Debrecen Musculoskeletal Symposium 2025.Osteoarthritis and cartilage open · 2026Article
- Joint pain and menopause.Menopause (New York, N.Y.) · 2026Article
- Global burden of gout attributable to high BMI (1990-2021) and causal link with obesity: a GBD and Mendelian randomization study.Therapeutic advances in endocrinology and metabolism · 2026Article
- Global Burden, Attributable Risk Factors, and Future Projections of Lower Extremity Peripheral Arterial Disease Among Postmenopausal Women.International journal of women's health · 2026Article
- The Impact of Population Aging on Ergonomic-Related Low Back Pain Across Regions with Different Development Levels.Journal of pain research · 2026Article
- The Role of Extracellular Vesicles in Musculoskeletal Diseases.Journal of extracellular vesicles · 2025Review
- Global, regional, and national burden of ischemic heart disease attributable to environmental risk factors from 1990 to 2021: a systematic analysis based on the 2021 global burden of disease study.Frontiers in public health · 2025Article
- Long-term trends and future projections of the burden of diabetic nephropathy in China: a comprehensive analysis of GBD data from 1990 to 2036.Frontiers in endocrinology · 2025Article
- Global, regional, and national burden of low back pain in postmenopausal women from 1990 to 2021: a comprehensive analysis using data from the Global Burden of Disease Study 2021.Frontiers in endocrinology · 2025Article
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12 authors.
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Abstract
backgroundThe global burden and trend of musculoskeletal disorders (MSDs) in postmenopausal women (PMW) remain unclear.
methodsUsing the Global Burden of Disease (GBD) 2021 data, this study assessed the prevalence and disability-adjusted life years (DALYs) for rheumatoid arthritis (RA), osteoarthritis (OA), low back pain (LBP), neck pain (NP), gout, and other musculoskeletal conditions (OMSKDs) from 1990 to 2021. Bayesian Age-Period-Cohort (BAPC) models projected trends to 2045. Health inequalities were analyzed using the Slope Index of Inequality (SII) and the Concentration Index, with decomposition methods identifying the drivers of burden changes.
resultsFrom 1990 to 2021, the age-standardized prevalence and DALYs rates have significantly increased among PMW, with OA and LBP being the primary contributors to this burden. These increases were primarily driven by population growth. Specifically, RA, OA, and gout accounted for more than 50% of the total burden in women across all age groups, with RA burden being 1.2 times higher than that in premenopausal women, OA 3.1 times higher, and gout 2.9 times higher. Notably, in PMW, the burden of gout was 74%. The burden of gout is strongly correlated with the Socio-Demographic Index (SDI), particularly in high-income regions, such as North America, where the United States exhibits the highest DALYs rates. Furthermore, projections indicate that by 2045, the global burden of MSDs could double, with OA potentially affecting nearly 50% of the PMW.
conclusionFrom 1990 to 2021, the global burden of MSDs among PMW has risen significantly, with notable regional disparities underscoring the critical need for tailored preventive strategies to alleviate the worldwide impact of these conditions.
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