ReviewEuropean journal of medical research2025
Risk factors and prognosis of post-surgical acute kidney injury in elderly patients based on the MIMIC-IV database.
Review in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Impact of area socioeconomic deprivation on major adverse renal events in patients with acute kidney injury: a retrospective cohort study of a single-center national patient population.Annals of medicine · 2026Article
- Preoperative eGFR, age, and sex predict early postoperative renal changes in acromegaly.Journal of the Endocrine Society · 2026Article
- Association between blood urea nitrogen-to-albumin ratio and postoperative acute kidney injury in patients undergoing off-pump coronary artery bypass grafting: a retrospective observational study.BMC cardiovascular disorders · 2026Observational
- Association between Creatinine Trajectories and All-Cause Mortality in Elderly Patients after Cardiac Surgery: A Retrospective Cohort Study Based on MIMIC-IV.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026Article
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Authors and funding
9 authors.
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Abstract
objectiveTo investigate the risk factors and prognosis of acute kidney injury (AKI) in elderly patients after surgery based on the Medical Information Mart for Intensive Care IV (MIMIC-IV).
methodsA retrospective analysis was conducted using MIMIC-IV data pertaining to aged postoperative patients. By logistic regression analysis models, Kaplan-Meier survival curve and Cox proportional hazards regression model. To evaluate the independent risk variables and prognosis of postoperative AKI in elderly patients.
resultsA total of 1784 elderly patients who met the inclusion criteria were analyzed. Among them, 1423 developed AKI after surgery. The development of AKI was significantly associated with the use of vasoactive drugs, invasive mechanical ventilation, traumatic surgical procedures, and elevated serum creatinine (Scr) levels within 24 h of admission. Cardiac surgery was also highly correlated with postoperative AKI. Factors associated with 28-day mortality in elderly patients with AKI included age ≥ 75 years, higher Sequential Organ Failure Assessment (SOFA) scores, elevated blood urea nitrogen (BUN) levels, presence of cerebrovascular disease (CVD), invasive ventilation, neurosurgical procedures, and traumatic surgical procedures.
conclusionsAge, Gender, Intervention measures and laboratory indicators can affect the incidence and prognosis of elderly patients' postoperative AKI. Early identification and timely intervention in patients with these high-risk factors are of practical significance in preventing the occurrence and progression of AKI.
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