Evidence map›Paper›PMID 40537753›Full record

ArticleBMC biotechnology2025

Exploring the mechanisms and mode of action of bioactive compounds from marine Streptomyces albidoflavus against breast carcinoma cells.

Abir M Shata, Mokhtar Saeed Rejili, Manal M El-Naggar, Samy A El-Asser, Ahmed A Saleh, Elsayed E Hafez, Faouzi Haouala, Amany S Youssef

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abir M Shata *National Institute of Oceanography and Fisheries, NIOF, Cairo, Egypt.
Mokhtar Saeed RejiliDepartment of Biology, College of Sciences, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia.
Manal M El-NaggarNational Institute of Oceanography and Fisheries, NIOF, Cairo, Egypt. mmelnaggar@yahoo.com.
Samy A El-AsserFaculty of Science, Department of Botany and Microbiology, Alexandria University, Alexandria, Egypt.
Ahmed A Saleh *College of Animal Science & Technology, Yangzhou University, Yangzhou, Jiangsu, 225009, China. Elemlak1339@gmail.com.
Elsayed E HafezDepartment of Plant Protection and Biomolecular Diagnosis, ALCRI City of Scientific Research and Technological Applications, Alexandria, Egypt.
Faouzi HaoualaDepartment of Biology, College of Sciences, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, 11623, Saudi Arabia.
Amany S YoussefFaculty of Science, Department of Botany and Microbiology, Alexandria University, Alexandria, Egypt.

Funding

The Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University (IMSIU) IMSIU-DDRSP2501
6 · The paper itself

Abstract

Breast cancer remains one of the most lethal diseases for women worldwide. Marine populations are considered a vast reservoir for novel bioactive metabolites, particularly marine Actinomycetes, which are known to produce various bioactive compounds with antitumour, antibacterial, and antifungal properties. A promising new marine strain was isolated and identified as Streptomyces albidoflavus strain EgyAB2 (16 S rRNA gene sequence accession number ON680945.1). The anticancer activity of the extracted compounds was tested in the MCF7 cell line using a sulforhodamine B (SRB) bioassay, which revealed an IC

Indexed as

Antineoplastic AgentsBreast NeoplasmsStreptomycesAntioxidantsApoptosisFemaleHumansMCF-7 CellsAntineoplastic AgentsAntioxidantsAnti-breast carcinomaApoptosisMarine StreptomycesMTTbioassaySRBbioassay

Identifiers

PMID40537753
PMCPMC12180265

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.