ReviewNature reviews. Nephrology2025
Effects of microplastics and nanoplastics on the kidney and cardiovascular system.
Review in Nature reviews. Nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Micro- and nanoplastics in the human genitourinary system: oncological impact - a systematic review.BJU international · 2026Pooled it
- Molecular and Cellular Effects of Microplastics and Nanoplastics in the Pathogenesis of Cardiovascular, Nervous, Urinary, Digestive, and Reproductive System Diseases: A Global Systematic Review.International journal of molecular sciences · 2025Pooled it
- Nanoplastics as disruptors of microtubule dynamics and intracellular trafficking: implications for cellular senescence and ageing.Molecular and cellular biochemistry · 2026Review
- Micro- and Nanoplastics in the Human Exposome: Environmental Pathways, Kidney Toxicity, and Implications for Public Health Risk Assessment.International journal of molecular sciences · 2026Review
- Microplastics and Nanoplastics in the Human Diet: Sources of Exposure, Bioavailability, Toxicokinetics, and Systemic Health Effects.Molecules (Basel, Switzerland) · 2026Review
- Micro- and Nanoplastic Pollution and Renal Health: Human Evidence, Mechanisms, and Clinical Implications.Journal of xenobiotics · 2026Review
- Untapped enzymatic potential: dehalogenase- and peroxidase-driven PVC degradation by gene carriers in Tibetan plateau pikas.Microbiome · 2026Article
- Applications of Stem Cells and Modern Toxicological Analytical Methods in the Toxicity of Microplastics.Toxics · 2026Review
- Tracing theEnvironment & health (Washington, D.C.) · 2026Article
- Micro-nanoplastics in Cardiovascular Disease: A Critical Update from Environmental Exposure to Clinical Implications.Cardiovascular toxicology · 2026Review
- Nano- and Microplastics in the Cardiovascular System: Current Insights and Biological Implications.Nanomaterials (Basel, Switzerland) · 2026Review
- Epidemiology of cardiovascular-kidney-metabolic syndrome.Nature reviews. Nephrology · 2026Review
- Effects of social determinants of health on the landscape of kidney disease.Nature reviews. Nephrology · 2026Review
- Cell-nanoplastics association impacts cell proliferation and motility.bioRxiv : the preprint server for biology · 2026Article
- Health impacts of micro- and nanoplastics: key influencing factors, limitations, and future perspectives.Archives of toxicology · 2026Review
- Micro- and Nanoplastics as a Potential Risk Factor for Stroke: A Systematic Review.Journal of xenobiotics · 2026Review
- Next-generation nanomaterials for environmental remediation: smart design, hybrid materials and sustainable use.Frontiers in chemistry · 2026Review
- Underexplored terrain: effects of high priority environmental toxicants on skeletal muscle.Journal of toxicology and environmental health. Part B, Critical reviews · 2026Review
- Sustainable Membrane Development: A Biopolymer Approach.Polymers · 2025Review
- Polyethylene microplastics disrupt renal function, mitochondrial bioenergetics, redox homeostasis, and histoarchitecture in Wistar rats.Scientific reports · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microplastics and nanoplastics are ubiquitous environmental pollutants that contaminate air, food and water supplies, resulting in widespread human exposure and potential health risks. Varying concentrations of particulate plastics have been identified in human tissues and body fluids, including the heart, kidney, liver, brain, blood and urine. Studies in animal models and human cells have reported that particulate plastics can induce oxidative stress, cell death and inflammation as well as disrupt metabolism and immune function. They have also been shown to have toxic effects on kidney and cardiovascular cells, which are exacerbated by the presence of other environmental contaminants such as heavy metals. Patients with kidney failure might be at risk of increased exposure to particulate plastics during dialysis. Furthermore, clinical evidence suggests that particulate plastic exposure is a risk factor for cardiovascular disease. Approaches to mitigating such exposure include degradation via abiotic and biotic processes, improved waste management and water filtration approaches and use of alternative materials. Further research into the fate, toxicity and health consequences of particulate plastics is imperative to inform strategies to address this escalating environmental and health concern.
Indexed as
Identifiers
40537559What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.