Evidence map›Paper›PMID 40537556›Full record

ArticleCommunications biology2025

Harmonizing network-based statistics across different atlases in brain connectome analysis.

Qingyuan Liu, Yongbin Wei, Dongxu Liu, Ting Qi, Kun Zhao, Ya-Hong Zhang, Long-Biao Cui, Yong Liu, Martijn P van den Heuvel

Abstract read
In one paragraph

Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qingyuan LiuCenter for Artificial Intelligence in Medical Imaging, School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.
Yongbin WeiCenter for Artificial Intelligence in Medical Imaging, School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China. yongbin.wei@bupt.edu.cn.ORCID http://orcid.org/0000-0002-8044-7667
Dongxu LiuCenter for Artificial Intelligence in Medical Imaging, School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.
Ting QiCenter for Artificial Intelligence in Medical Imaging, School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.
Kun ZhaoCenter for Artificial Intelligence in Medical Imaging, School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.
Ya-Hong ZhangDepartment of Psychiatry, Xi'an Gaoxin Hospital, Xi'an, China.
Long-Biao CuiShaanxi Provincial Key Laboratory of Clinic Genetics, Fourth Military Medical University, Xi'an, China.ORCID http://orcid.org/0000-0002-0784-181X
Yong LiuCenter for Artificial Intelligence in Medical Imaging, School of Artificial Intelligence, Beijing University of Posts and Telecommunications, Beijing, China.ORCID http://orcid.org/0000-0002-1862-3121
Martijn P van den HeuvelDepartment of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID http://orcid.org/0000-0003-1570-1195

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
National Natural Science Foundation of China (National Science Foundation of China) 82202264Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) 7232341NIMH NIH HHS U54 MH091657
6 · The paper itself

Abstract

Incorporating summary statistics across neuroimaging studies is important for enhancing translatability but poses challenges to connectomic analyses due to diverse methodological pipelines and brain atlases. We present TACOS (Transform brAin COnnectomes across atlaSes), a novel tool that translates network-based statistics across different atlases without requiring individual raw data. TACOS employs linear models based on anatomical information from brain parcellations and white matter fibers. Testing across 17 atlases, we show TACOS-transformed t-statistics to correlate well to the ground truth for both structural (r = 0.32-0.95) and functional networks (r = 0.57-0.95) using HCP surrogate statistics. These correlations remain consistent when tested with independent data from populations of different ancestries. Furthermore, TACOS effectively harmonizes connectomic results across multi-site schizophrenia data cohorts (r = 0.57-0.94 and 0.75-0.95 for structural and functional networks, respectively). This tool enables cross-atlas transformations of network-based statistics, showing great potential for downstream applications that share and combine multi-site connectomic data.

Indexed as

Atlases as TopicBrainConnectomeNerve NetFemaleHumansMagnetic Resonance ImagingMaleNeuroimagingSchizophrenia

Identifiers

PMID40537556
PMCPMC12179274

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.