ArticlePediatric cardiology2026
Effect of Transcatheter Closure of the Ductus Arteriosus on Right Ventricular Function in Preterm Neonates.
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Factors Influencing Prolonged Hospital Stay in Surgically Treated Children and Adolescents with Left-to-Right Shunt Congenital Heart Disease: Evidence From a Hospital in Southern China.Therapeutics and clinical risk management · 2025Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA large non-restricted left-to-right shunt across a patent ductus arteriosus (PDA) with the resultant volume and pressure load may impact right ventricle (RV) function. We aimed to compare RV function on echocardiogram before and soon after transcatheter closure of PDA in preterm neonates.
methodThis single-center retrospective study included preterm infants ≤ 2 kg who underwent PDA transcatheter closure. Echocardiograms before and within 24 h after transcatheter closure were analyzed by a single reader for i) Tricuspid Annular Plane systolic excursion (TAPSE), ii) RV Velocity Time Integral (VTI) outflow, iii) RV Fractional area change (FAC), iv) Systolic-to-diastolic time (SD) ratio from the tricuspid valve regurgitation, and v) Stroke distance, the product of VTI and heart rate. Paired t test was used to compare parameters before and after device closure.
resultsOur cohort (n = 97), 54.6% of whom were males, had a mean (Standard Deviation) gestational age of 24.9 (1.9) weeks and birth weight of 742 (244) grams. The median (IQR) age at procedure was 29 (21-45) days. We found evidence of RV dysfunction (abnormal TAPSE in 14%, FAC in 66.5% and SD in 100%) at baseline with significant improvement 24 h after device closure in RV VTI, FAC, SD, stroke distance, and myocardial performance index.
conclusionAmong preterm infants with a PDA, transcatheter closure was associated with significant short-term improvement in RV systolic function. These data provide novel intriguing insights into the potential benefit of unloading of the RV through device closure in this population.
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