Evidence map›Paper›PMID 40537503›Full record

ArticleNPJ digital medicine2025

A health digital twin framework for discrete event simulation based optimised critical care workflows.

Gayan Dihantha Kuruppu Kuruppu Appuhamilage, Maqbool Hussain, Mohsin Zaman, Wajahat Ali Khan

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Mapping the future of medicine through digital twins.Frontiers in molecular medicine · 2026
    Review
  9. Analysis of digital twin applications in nursing practice and education: a scoping review.Journal of educational evaluation for health professions · 2026
    Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gayan Dihantha Kuruppu Kuruppu Appuhamilage *School of Computing, College of Science and Engineering, University of Derby, Kedleston Road, Derby, UK, DE22 1GB.
Maqbool Hussain *School of Computing, College of Science and Engineering, University of Derby, Kedleston Road, Derby, UK, DE22 1GB. m.hussain@derby.ac.uk.
Mohsin Zaman *Northampton General Hospital NHS Trust, Cliftonville, Northampton, UK, NN1 5BD.
Wajahat Ali KhanSchool of Computing, College of Science and Engineering, University of Derby, Kedleston Road, Derby, UK, DE22 1GB.

Funding

NOETIC LTD PSL2324-0100University of Derby PSL2324-0100
6 · The paper itself

Abstract

Digital twins have been used in industries and is now gaining traction in healthcare, particularly in precision medicine. Discrete Event Simulation is a modelling methodology for simulating processes and workflows in healthcare. This paper presents a methodology that integrates these technologies to optimise critical care workflows based on real-time state changes, emphasising patient safety, operational efficiency, and sustainability. This study proposes a novel dual-layer architecture to monitor physical and conceptual entities in the Critical Care Unit. In the current scope, this study aims to establish a methodology using Azure cloud to track treatment workflows in real-time. The results indicated that by reviewing observation forms alone successfully tracked 72% of staff-performed tasks in real-time. This study underscores the potential of digital twins to transform precision care in critical care delivery by bridging the gap between actual and ideal clinical practices.

Identifiers

PMID40537503
PMCPMC12179303

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.