ArticleBMJ open2025
Uptake of the IMMPACT-recommended core outcome set in randomised controlled trials on chronic neck or shoulder pain: a cross-sectional study.
Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Authors and funding
5 authors.
Funding
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Abstract
objectiveTo analyse the uptake rate of Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials (IMMPACT)-recommended core outcome set (COS) in randomised controlled trials (RCTs) on chronic neck or shoulder pain and its potential influencing factors.
designA cross-sectional study.
settingWHO International Clinical Trials Registry Platform, involving 15 registries.
participantsRCT registrations on chronic neck or shoulder pain. PRIMARY OUTCOME MEASURES: The uptake rate of IMMPACT-recommended COS in RCTs focusing on chronic neck or shoulder pain.
resultsA total of 1057 RCT registrations were included between 2 February 2004 and 8 February 2023. The most used domains were pain (n=1003, 94.9%) and physical functioning (n=971, 91.9%), while the remaining four core domains and supplementary domains received less attention (<10%), exhibiting either a downward trend or an initial increase followed by a decrease. Univariable and multivariable analyses did not indicate consistent, significant differences in various outcome domains in RCTs categorised according to the study period, blinding and prospective registration statuses, follow-up duration and sample size.
conclusionsAlthough the pain and physical functioning domains were widely reported by RCTs on chronic neck or shoulder pain since the publication of IMMPACT-recommended COS, the uptake rate was low for other domains and outcome measures. The study period, blinding status, prospective registration, follow-up duration and sample size may influence COS uptake across domains. TRIAL REGISTRATION NUMBER: http://www.comet-initiative.org/Studies/Details/3213.
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