ArticleBritish journal of anaesthesia2025
Maternal fever, epidural analgesia, and genetics: implications for the neonate.
Article in British journal of anaesthesia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Induction of Labour with Prostaglandins: Does Their Pro-Inflammatory Effect Mimic Chorioamnionitis After PROM?Geburtshilfe und Frauenheilkunde · 2026Article
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Authors and funding
3 authors.
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Abstract
Epidural-related maternal fever affects 15-25% of labouring women, but its mechanisms remain uncertain. In a prospective observational study, the EPIFEVER-2 investigators found no firm link between interleukin-1Ra concentrations and epidural-related maternal fever, suggesting other aetiological factors. Clinically, the main challenge lies in distinguishing epidural-related maternal fever from infectious fever to avoid unnecessary antibiotic use and neonatal interventions. Despite the increased risk of fever in women receiving epidural analgesia, there is no strong evidence of harm to the newborn, and women should be supported in making informed decisions about pain relief without undue concern over potential neonatal complications.
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