ArticleThe clinical respiratory journal2025
ECG Abnormalities and Biomarkers Enable Rapid Risk Stratification in Normotensive Patients With Acute Pulmonary Embolism.
Article in The clinical respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Prognostic Value of Troponin in Acute Pulmonary Embolism: A Systematic Review and Meta-Analysis.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2025Pooled it
- Artificial Intelligence-Driven Integration of ECG and Molecular Biomarkers in Pulmonary Embolism.International journal of molecular sciences · 2026Review
- The Hidden Signal: P Wave Morphology and In-Hospital Mortality in Acute Pulmonary Embolism.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe patients with suspected pulmonary embolism (PE) were usually screened using electrocardiogram (ECG) and blood panel of D-dimer, troponin, and blood gas analysis in the emergency.
objectivesThis study aimed to explore a rapid risk model to predict in-hospital adverse events for normotensive PE patients.
methodsPatients with acute PE having normal blood pressure on appearance were retrospectively enrolled at China-Japan Friendship Hospital from January 2017 to February 2020. The in-hospital adverse events were defined as death and clinical deterioration during hospitalization. The risk model for in-hospital adverse events was generated by multivariate regression analysis. The discrimination ability of the model was compared with PESI, Bova, and FAST risk score, and evaluated by the receiver operating characteristic curve (ROC), net reclassification improvement (NRI), and integrated discrimination improvement index (IDI).
resultsOf the 213 patients, 35 (16.4%) experienced in-hospital adverse events,y including 15 deaths. The average age was 69 ± 19 years, and 118 (44.6%) were females. Multiple logistic regression analysis showed that independent risk factors associated with in-hospital adverse events were low QRS voltage in ECG (OR: 5.321; 95% CI: 1.608-7.310), positive age-adjusted D-dimer (OR: 2.061; 95% CI: 0.622-6.836), positive troponin (OR: 3.504; 95% CI: 1.744-8.259), and PaO
conclusionECG abnormalities and biomarkers on admission may provide a rapid and effective approach to identify patients with poor prognoses during hospitalization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.