Evidence map›Paper›PMID 40536574›Full record

Trial reportEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025

Efficacy of platelet-rich plasma in grade 2 hamstring muscle injuries: results from a randomized controlled trial.

Clevio Desouza, Vijay Shetty

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Epidemiology, Work-Up, and Management of Common Track and Field Injuries.Current reviews in musculoskeletal medicine · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Clevio DesouzaSAANVI Orthopaedics, Mumbai, India. ceviod@gmail.com.
Vijay ShettySAANVI Orthopaedics, Mumbai, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHamstring injuries are a major cause of time-loss in athletes, often leading to prolonged recovery and high recurrence rates. This randomized controlled trial evaluated the efficacy of ultrasound-guided platelet-rich plasma (PRP) injections in accelerating return to play (RTP) and enhancing radiological healing in grade 2 hamstring injuries.

methodsSixty athletes with MRI-confirmed grade 2 hamstring injuries were randomized into two groups: PRP plus standard therapy (n = 30) and standard therapy alone (n = 30). All followed a standardized rehabilitation protocol. Primary outcome was time to return to play (TTRTP). Secondary outcomes included MRI healing at 21 days, re-injury rates, and adverse events, with a 2-year follow-up.

resultsThe PRP group showed significantly faster RTP (26.4 ± 4.5 vs. 34.2 ± 5.7 days; p < 0.001) and greater MRI healing at 21 days (70% vs. 36.7%; p = 0.003). Re-injury rates were lower in the PRP group (3.3% vs. 16.7%), though not statistically significant (p = 0.09). No adverse events were reported.

conclusionUltrasound-guided PRP injection with standard rehabilitation accelerates return to play and improves radiological healing in acute grade 2 hamstring injuries, representing a safe and promising adjunct in sports injury management.

Indexed as

Athletic InjuriesHamstring MusclesPlatelet-Rich PlasmaAdolescentAdultFemaleHumansInjections, IntramuscularMagnetic Resonance ImagingMaleReturn to SportTreatment OutcomeUltrasonography, InterventionalWound HealingYoung AdultHamstring injuryPlatelet-rich plasmaRehabilitationReturn to playSports medicine

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.