Observational studyJournal of robotic surgery2025
Robotic thymectomy for large thymomas: a multicenter study.
Observational study in Journal of robotic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Reply to "Robotic thymectomy for large thymomas: considering the impact of residual tumor complexity" and comment on "Robotic thymectomy for large thymomas: a multicenter study".Journal of robotic surgery · 2026Article
- A Shift from Standard Median Sternotomy to Robotic-Assisted Thoracic Surgery for Resection of Anterior Mediastinal Tumors.Journal of clinical medicine · 2026Article
- Robotic-assisted thymectomy for locally advanced thymic malignancy: technical refinement and oncologic outcomes from a 20-year cohort.Journal of thoracic disease · 2025Article
- Comment on "Robotic thymectomy for large thymomas: a multicenter study".Journal of robotic surgery · 2025Article
- Robotic thymectomy for large thymomas: considering the impact of residual tumor complexity.Journal of robotic surgery · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to evaluate surgical and oncological outcomes of robot-assisted (RATS) thymectomy in the treatment of large (diameter > = 5 cm) resectable thymomas. Clinical data of 301 thymectomies for thymoma, performed in 7 high-volume centers from 2010 to 2023, were retrospectively reviewed. 132 RATS thymectomies were performed: 59 (44.7%) for small and 73 (55.3%) for large thymomas. Conversion (p = 0.48), significant complications (p = 0.26), and hospital stay (p = 0.79) were similar in both groups. Overall, 191 large thymomas were operated on: 73(38.2%) by RATS, 118 (61.8%) by open approach. Comparing the RATS approach with the open standard approach for the treatment of large thymomas, more post-operative complications (p < 0.001) but similar major complications (p = 0.11) and a longer in-hospital stay (p < 0.001) were recorded in the open group. Five-year OS (95% vs 85%, p = 0.14) and DFS (86 vs 93%, p = 0.18) of patients affected by large thymomas were comparable between RATS and the open group. To minimize selection-confounding factors between the two large thymoma groups (RATS vs open) in relation to the outcomes, a 1:1 propensity score match (PSM) analysis was performed, and surgical and oncological outcomes reassessed. Chest tube length (p < 0.001) and in-hospital stay (p < 0.001) were confirmed to be longer in the open group. Prognostic factors for oncological outcomes for large thymomas were also confirmed after PSM analysis. Adjuvant radiotherapy was the only predictive factor (p = 0.033) affecting DFS, while no factor was confirmed for OS at multivariable analysis. RATS seems to be a safe and effective alternative to open surgery for treating large thymomas.
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