Evidence map›Paper›PMID 40536546›Full record

ArticleMolecular biology reports2025

Comparative analysis of the mitochondrial genome of Carpodacus erythrinus (Passeriformes: Fringillidae) across different altitudes.

Yu Zhang, Wenshu Zhang, Fan Zhang, Shaobin Li

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yu ZhangCollege of Life Sciences, Yangtze University, Jingzhou, Hubei, 434025, China.
Wenshu ZhangCollege of Life Sciences, Yangtze University, Jingzhou, Hubei, 434025, China.
Fan ZhangCollege of Life Sciences, Yangtze University, Jingzhou, Hubei, 434025, China.
Shaobin LiCollege of Life Sciences, Yangtze University, Jingzhou, Hubei, 434025, China. shaobinli@yangtzeu.edu.cn.

Funding

the National Natural Sciences Foundation of China 32170481 and 32470496
6 · The paper itself

Abstract

backgroundTo investigate the genetic basis of high-altitude adaptation in animals from the Tibetan Plateau, we sequenced the mitochondrial genome of the common rosefinch (Carpodacus erythrinus) collected from Xiahe County (3200 m) in the northeastern Tibetan Plateau. We conducted comparative analysis with mitochondrial genomes of conspecific individuals from lower-elevation areas. METHODS AND

resultsThe complete mitochondrial genome is 16,824 bp in length. Divergence time analysis indicates that C. erythrinus diverged from its common ancestor with other Carpodacus species approximately 16.21 million years ago, coinciding with the timing of the fourth uplift of the Tibetan Plateau. We compared the mitochondrial genome of C. erythrinus from Xiahe County with sequences obtained from Hawaii (1680 m) and Denmark (30 m), revealing only slight variations in sequence lengths among individuals at different altitudes. With the exception of ATP8, all protein-coding genes (PCGs) exhibited a similarity exceeding 99% at both nucleotide and amino acid levels. Analysis of mitochondrial PCGs revealed that ND5 contained the highest number of mutation sites and non-synonymous mutations. The Ka/Ks ratios for all mitochondrial PCGs were found to be less than 1, indicating that these genes have undergone purifying selection. In summary, the mitochondrial genome exhibits a remarkable degree of conservation, characterized by a stable gene structure and low mutation rates.

conclusionsThe mitochondrial genome of C. erythrinus serves as an important genomic resource for conservation efforts concerning this species and provides valuable insights into adaptive evolution within mitochondrial PCGs, particularly regarding avian adaptations to high altitudes.

Indexed as

AltitudeGenome, MitochondrialPasseriformesAnimalsEvolution, MolecularPhylogenySequence Analysis, DNATibetCarpodacus erythrinusComparative analysisDivergence timeHigh-altitude adaptationMitochondrial genome

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