Evidence map›Paper›PMID 40536409›Full record

ArticleJournal of studies on alcohol and drugs2026

Cognitive Bias Modification for Individuals With Opioid Use Disorder and Chronic Pain Did Not Predict Changes in Clinical Outcomes.

Noah R Wolkowicz, Brian Pittman, Shannon W Schrader, Danielle M Wesolowicz, Mehmet Sofuoglu, Alicia A Heapy, Ross R Maclean

Abstract read
In one paragraph

Article in Journal of studies on alcohol and drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Noah R WolkowiczVeterans Affairs Connecticut Healthcare System, West Haven, Connecticut.
Brian PittmanYale University School of Medicine, New Haven, Connecticut.
Shannon W SchraderVeterans Affairs Connecticut Healthcare System, West Haven, Connecticut.
Danielle M WesolowiczVeterans Affairs Connecticut Healthcare System, West Haven, Connecticut.
Mehmet SofuogluVeterans Affairs Connecticut Healthcare System, West Haven, Connecticut.
Alicia A HeapyVeterans Affairs Connecticut Healthcare System, West Haven, Connecticut.
Ross R MacleanVeterans Affairs Connecticut Healthcare System, West Haven, Connecticut.

Funding

CSRD VA IK2 CX002286
6 · The paper itself

Abstract

objectiveAttentional bias, defined as the preferential focus on personally salient--compared with neutral--cues, has a hypothesized link to substance use disorders and chronic pain. Although growing research demonstrates that cognitive bias modification (CBM) can alter attentional biases, evidence is lacking to assess the extent to which such alterations predict changes in clinical symptoms or behaviors (e.g., pain severity, craving).

methodWe conducted a secondary analysis of a clinical trial examining the feasibility, acceptability, and preliminary effectiveness of a 4-week CBM adjunct for veterans (

resultsCBM for opioid and pain cues did not correspond with changes in the primary clinical outcomes of opioid craving and pain intensity (

conclusionsResults from this pilot study did not show changes in pain severity or opioid craving corresponding to CBM for opioid and pain. Findings should be considered preliminary given our small sample size; however, findings indicate a distinction between attentional biases, their modification, and clinically salient outcomes. Future research should examine CBM in larger, more diverse samples and assess the impacts of addiction severity, substance type, naturalistic settings, and more engaging methodologies (e.g., gamification of CBM tasks, using gaze-contingent paradigms).

Indexed as

Attentional BiasChronic PainCognitive Behavioral TherapyOpioid-Related DisordersAdultCatastrophizationCravingFemaleHumansMaleMiddle AgedPain MeasurementPilot ProjectsTreatment OutcomeVeterans

Identifiers

PMID40536409
PMCPMC12569794

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.