Evidence map›Paper›PMID 40536332›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

H3K36me3-Guided m

Teng Wang, Linyu Han, Yanfei Huo, Long Zhang, Yizhou Huang, Nasha Zhang, Ming Yang

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
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  4. Article
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  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Teng WangShandong University Cancer Center, Jinan, Shandong Province, 250100, China.ORCID https://orcid.org/0000-0002-2931-8181
Linyu HanShandong Provincial Key Laboratory of Precision Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Jinan, Shandong Province, 250117, China.
Yanfei HuoShandong Provincial Key Laboratory of Precision Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Jinan, Shandong Province, 250117, China.
Long ZhangShandong Provincial Key Laboratory of Precision Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Jinan, Shandong Province, 250117, China.
Yizhou HuangShandong Provincial Key Laboratory of Precision Oncology, Cancer Research Center, Shandong Cancer Hospital and Institute, Jinan, Shandong Province, 250117, China.
Nasha ZhangDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, Shandong Province, 250117, China.
Ming YangShandong University Cancer Center, Jinan, Shandong Province, 250100, China.ORCID https://orcid.org/0000-0003-0310-5839

Funding

Collaborative Academic Innovation Project of Shandong Cancer Hospital TS008Major Scientific and Technological Innovation Project of Shandong Province 2021ZDSYS04National Natural Science Foundation of China 82103291National Natural Science Foundation of China 82173070National Natural Science Foundation of China 82303135National Natural Science Foundation of China 82372760Natural Science Foundation of Shandong Province ZR202102250889Natural Science Foundation of Shandong Province ZR2021LZL004Natural Science Foundation of Shandong Province ZR202211010077Natural Science Foundation of Shandong Province ZR2024MH099Taishan Scholars Program of Shandong Province tsqn202211340Taishan Scholars Program of Shandong Province tstp20221141Wellcome Trust 202404
6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most lethal malignancies and epigenetic modifiers play a key role in HCC progression. Histone H3 trimethylation at lysine-36 (H3K36me3) determines deposition of mRNA de novo N

Indexed as

Carcinoma, HepatocellularHistonesLiver NeoplasmsMacrophagesRNA, Long NoncodingAdenosineAnimalsCell Line, TumorGene Expression Regulation, NeoplasticHumansImmunotherapyMiceAdenosineHistonesN-methyladenosineRNA, Long NoncodingH3K36me3hepatocellular carcinomaimmunotherapy resistanceL1CAM‐AS1m6Amacrophage polarization

Identifiers

PMID40536332
PMCPMC13001626

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.