ArticleHuman brain mapping2025
Structural White Matter Correlates of the Crowding Effect: Insights From a Tractography Study of the Arcuate Fasciculus Post-Hemispherotomy.
Article in Human brain mapping, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Structural White Matter Correlates of the Crowding Effect: Insights From a Tractography Study of the Arcuate Fasciculus Post-Hemispherotomy.Human brain mapping · 2025Article
- RapidParc: A global-context transformer for parallel, accurate, and lesion-robust tractogram parcellation.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
The neuropsychological crowding effect denotes the reallocation of cognitive functions within the contralesional hemisphere following unilateral brain damage, prioritizing language at the expense of nonverbal abilities. This study investigates structural white matter correlates of crowding in the arcuate fasciculus (AF), a key language tract, using hemispherotomy as a unique setting to explore structural reorganization supporting language preservation. We explore two main hypotheses. First, the contralesional right AF undergoes white matter reorganization correlated with preserved language function at the expense of nonverbal abilities following left-hemispheric damage. Second, this reorganization varies with epilepsy etiology, influencing different stages of developmental language lateralization. This retrospective study included individuals post-hemispherotomy and healthy controls. Inclusion criteria were; (1) being a native German speaker, (2) having no MRI contraindication, (3) the ability to undergo approximately 2 h of MRI scans, and (4) the ability to participate in neuropsychological assessments over two consecutive days. Neuroimaging included T1-, T2-, and diffusion-weighted imaging, alongside postoperative neuropsychological assessments, where it was taken as evidence for crowding if verbal IQ exceeded performance IQ by at least 10 points. The AF was reconstructed using advanced tractography, and CoBundleMAP was used to compare morphologically corresponding AF subsections. Statistical significance was set at
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Registered trials
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