Evidence map›Paper›PMID 40536166›Full record

ArticleBiochemistry2025

A Pair of Promiscuous Surrogates for

Carley Z Reid, Allison N Dombroski, Vitalii S Basistyi, Kevin K Desai, Brian G Miller

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carley Z ReidDepartment of Chemistry and Biochemistry, Laboratories of Molecular Recognition, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.
Allison N DombroskiDepartment of Chemistry and Biochemistry, Laboratories of Molecular Recognition, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.
Vitalii S BasistyiDepartment of Chemistry and Biochemistry, Laboratories of Molecular Recognition, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.
Kevin K DesaiRevel Pharmaceuticals, 2325 third Street, San Francisco, California 94107, United States.
Brian G MillerDepartment of Chemistry and Biochemistry, Laboratories of Molecular Recognition, Florida State University, 95 Chieftan Way, Tallahassee, Florida 32306, United States.ORCID 0000-0002-6624-0344

Funding

Evolutionary Origins of Protein RegulationR01GM133843 · NIGMS · FLORIDA STATE UNIVERSITY · PI MILLER, BRIAN GENE · 2019 to 2022
$1.2M
NIGMS NIH HHS R01 GM133843
6 · The paper itself

Abstract

The identification and characterization of promiscuous enzymes is significant because they provide the raw materials for evolving new catalysts and assembling new metabolic pathways. Here, we report the discovery of two promiscuous enzymes from

Indexed as

Amino-Acid N-AcetyltransferaseArginineAspartate CarbamoyltransferaseEscherichia coliEscherichia coli ProteinsGlutamatesAmino-Acid N-AcetyltransferaseArginineAspartate CarbamoyltransferaseEscherichia coli ProteinsGlutamatesN-acetylglutamic acid

Identifiers

PMID40536166
PMCPMC12556938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.