Evidence map›Paper›PMID 40536117›Full record

ReviewJournal of cosmetic dermatology2025

The Role of Tyrosine Kinase in Beauty and Skincare: A Comprehensive Review.

Zhongxia Li

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Zhongxia LiShenzhen Academy of Metrology & Quality Inspection, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTyrosine kinases (TKs) are integral enzymes crucial for regulating cellular processes such as growth, differentiation, and metabolism, with significant implications in dermatology.

aimsThis review aims to provide a comprehensive analysis of TKs' role in dermatological conditions, focusing on pigmentation, aging, and inflammation. It seeks to elucidate the mechanisms through which TKs modulate these processes to advance understanding of their therapeutic potential.

methodsThe review analyzes recent studies on the effects of tyrosine kinase inhibitors (TKIs) on pigmentation and skin elasticity, highlighting their potential in reducing hyperpigmentation and improving skin elasticity. It also considers the challenges faced in the clinical application of TKIs, such as variable efficacy and potential side effects.

resultsRecent studies show that TKIs can reduce pigmentation by up to 30% in specific hyperpigmentation disorders and improve skin elasticity by approximately 15% in anti-aging applications. However, challenges include variable efficacy across patient populations and potential side effects like skin irritation or systemic toxicity.

conclusionsThis review advances our understanding of TKs' therapeutic potential in dermatology. However, overcoming challenges such as variable efficacy and side effects is essential to optimize the application of TKIs in skincare. Further research is needed to develop more effective and safer TKIs tailored to specific dermatological conditions.

Indexed as

BeautyHyperpigmentationProtein Kinase InhibitorsProtein-Tyrosine KinasesElasticityHumansSkinSkin AgingSkin CareSkin PigmentationProtein Kinase InhibitorsProtein-Tyrosine Kinasesagecosmeceuticalsdermatitisepidermal growth factorsskin caretyrosinase inhibition

Identifiers

PMID40536117
PMCPMC12177907

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.