Evidence map›Paper›PMID 40535814›Full record

ArticleJournal of Cancer2025

Two-Sample Network Mendelian Randomization and Single-Cell Analysis Reveal the Causal Associations and Underlying Mechanisms Between Antihypertensive Drugs and Kidney Cancer.

Ruiyi Deng, Mingrui Zou, Jianhui Qiu, Jiaheng Shang, Chaojian Yu, Peidong Tian, Yizhou Wang, Lin Cai, Jingcheng Zhou, Kan Gong

Abstract read
In one paragraph

Article in Journal of Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ruiyi DengDepartment of Urology, Peking University First Hospital, Beijing, China.
Mingrui ZouDepartment of Urology, Peking University First Hospital, Beijing, China.
Jianhui QiuDepartment of Urology, Peking University First Hospital, Beijing, China.
Jiaheng ShangDepartment of Urology, Peking University First Hospital, Beijing, China.
Chaojian YuDepartment of Urology, Peking University First Hospital, Beijing, China.
Peidong TianDepartment of Urology, Peking University First Hospital, Beijing, China.
Yizhou WangDepartment of Central Laboratory, Peking University First Hospital, Beijing, China.
Lin CaiDepartment of Urology, Peking University First Hospital, Beijing, China.
Jingcheng ZhouDepartment of Urology, Peking University First Hospital, Beijing, China.
Kan GongDepartment of Urology, Peking University First Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antihypertensive drugsdrug targetkidney cancerMendelian randomizationsingle-cell analysis

Identifiers

PMID40535814
PMCPMC12170992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.