Evidence map›Paper›PMID 40535663›Full record

ArticleAmerican journal of translational research2025

Clinical and radiologic evaluation of the IntraSPINE non-fusion technique for lumbar degenerative disease.

Yang Li, Si-Peng Li, Ming-Zuo Guo, Lai-Zhou Ji, Meng Chen, Da-Yong Peng, Wen-Xiu Hou, Hao-Xuan Zhang

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang LiDepartment of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University No. 16766 Jingshi Road, Jinan 250014, Shandong, China.
Si-Peng LiDepartment of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University No. 16766 Jingshi Road, Jinan 250014, Shandong, China.
Ming-Zuo GuoDepartment of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University No. 16766 Jingshi Road, Jinan 250014, Shandong, China.
Lai-Zhou JiDepartment of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University No. 16766 Jingshi Road, Jinan 250014, Shandong, China.
Meng ChenDepartment of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University No. 16766 Jingshi Road, Jinan 250014, Shandong, China.
Da-Yong PengDepartment of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University No. 16766 Jingshi Road, Jinan 250014, Shandong, China.
Wen-Xiu HouDepartment of Spine Surgery, Shandong University Qilu Hospital Jinan 250000, Shandong, China.
Hao-Xuan ZhangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Shandong First Medical University No. 16766 Jingshi Road, Jinan 250014, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the clinical and radiographic outcomes of the non-fusion IntraSPINE technique with patients receiving traditional lumbar fusion.

methodsA prospective study was conducted on patients with lumbar degenerative disease who failed to respond to conservative treatment. Clinical and radiologic evaluations were performed preoperatively and at 7 days, 6 months, and 12 months postoperatively. Clinical outcomes were assessed using the Japanese Orthopaedic Association (JOA) score, Visual Analogue Scale (VAS), and Oswestry Disability Index (ODI). Radiographic parameters included range of motion (ROM), posterior disc height (PDH), and foraminal height (FH) at the treated and adjacent segments.

resultsBoth groups demonstrated significant postoperative improvements in VAS, JOA, and ODI scores. However, the fusion group demonstrated complete loss of motion at the treated segment and increased motion at adjacent segments. In contrast, the non-fusion group retained partial ROM at the treated segment while maintaining adjacent segment motion close to preoperative levels. PDH and FH remained stable in the non-fusion group, whereas the fusion group experienced significant reductions in these measures at the adjacent segments.

conclusionThe IntraSPINE non-fusion technique yields clinical outcomes comparable to those of lumbar fusion, while preserving ROM, PDH, and FH in both the treated and adjacent segments. This preservation may reduce the risk of adjacent segment degeneration, supporting the use of IntraSPINE as a viable alternative to traditional fusion surgery.

Indexed as

Degenerative disease of the lumbar spineIntraSPINE dynamic stabilization systemlumbar fusionnon-fusion

Identifiers

PMID40535663
PMCPMC12170381

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.