Evidence map›Paper›PMID 40535660›Full record

ArticleAmerican journal of translational research2025

Endovascular therapy for iliac vein compression syndrome: superior outcomes in non-thrombotic patients and risk factors for stent restenosis.

Zhongyin Wu, Kewu He, Xiaozheng Peng, Wanli Lin

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Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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4 authors.

Zhongyin WuDepartment of Interventional Vascular Surgery, Hefei First People's Hospital Hefei 230000, Anhui, China.
Kewu HeDepartment of Interventional Vascular Surgery, Hefei First People's Hospital Hefei 230000, Anhui, China.
Xiaozheng PengDepartment of Interventional Vascular Surgery, Hefei First People's Hospital Hefei 230000, Anhui, China.
Wanli LinDepartment of Interventional Vascular Surgery, Hefei First People's Hospital Hefei 230000, Anhui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the long-term efficacy and thrombotic outcomes of endovascular therapy for iliac vein compression syndrome (IVCS), with a focus on identifying risk factors for postoperative stent restenosis.

methodsThis retrospective cohort study analyzed 98 IVCS patients treated with endovascular therapy at Hefei First People's Hospital between January 2020 and December 2022. Patients were divided into non-thrombotic (NIVCS, n=48) and acute thrombotic (TIVCS, n=50) groups. Outcomes included 1-year stent patency, complications, and quality-of-life metrics (CIVIQ-20 and VCSS scores). Logistic regression was used to identify risk factors for restenosis, with diagnostic performance accessed via ROC analysis.

resultsThe NIVCS group demonstrated significantly better 1-year stent patency (91.67% vs. 74%, P=0.018) but higher complication rates (20% vs. 8.33%, P=0.025) compared to the TIVCS group. Both groups showed significant improvements in CIVIQ-20 and VCSS scores (P<0.05), with NIVCS patients achieving better final outcomes. Multivariate analysis identified thrombotic IVCS (OR=3.41, 95% CI: 1.28-9.07), body mass index ≥28 kg/m

conclusionEndovascular therapy effectively improves symptoms and quality of life in IVCS, particularly in non-thrombotic cases. The thrombotic subtype, obesity, and hypertension significantly influence long-term stent patency, highlighting the need for personalized postoperative management. These findings underscore the potential of risk-stratified therapeutic strategies in vascular interventions.

Indexed as

deep vein thrombosisendovascular therapyIliac vein compression syndromerisk stratificationstent restenosis

Identifiers

PMID40535660
PMCPMC12170425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.