Evidence map›Paper›PMID 40535644›Full record

ArticleAmerican journal of translational research2025

Construction of a clinical predictive model for risk factors after laparoscopic surgery in patients with endometriosis based on pathologic characteristics.

Fang Li, Yunxiu Fan, Yanni Huang, Juan Yan, Hui Yang, Xin Yang, Wenli Qiao, Hua Chen, Haifeng Jiang, Na Zhao

Abstract read
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Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Fang LiDepartment of Pathology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.
Yunxiu FanDepartment of Pediatrics, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.
Yanni HuangDepartment of Gynaecology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.
Juan YanDepartment of Gynaecology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.
Hui YangDepartment of Pathology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.
Xin YangDepartment of Gynaecology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.
Wenli QiaoDepartment of Gynaecology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.
Hua ChenDepartment of Gynaecology, General Hospital of Ningxia Medical University Yinchuan 750004, Ningxia, China.
Haifeng JiangDepartment of Pathology, General Hospital of Ningxia Medical University Yinchuan 750004, Ningxia, China.
Na ZhaoDepartment of Gynaecology, Peking University First Hospital Ningxia Women and Children's Hospital (Ningxia Hui Autonomous Region Maternal and Child Health Hospital) Yinchuan 750001, Ningxia, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the correlation between preoperative pathologic characteristics and the risk of postoperative recurrence in endometriosis (EMs) patients, and to develop a clinical predictive model.

methodsA retrospective analysis was conducted on 164 EMs patients who underwent laparoscopic surgery between January 2022 and December 2023 at Peking University First Hospital Ningxia Women and Children's Hospital. Demographic and clinicopathologic data were collected, and patients were stratified by one-year recurrence status. Multivariable logistic regression identified independent recurrence risk factors, and a predictive nomogram was constructed. Model performance was evaluated using ROC curves, the Hosmer-Lemeshow goodness-of-fit test (HLGOF), calibration curves, and decision curve analysis.

resultsPostoperative recurrence occurred in 46 patients (28%) within one year. Univariate analysis revealed associations between recurrence and factors including dysmenorrhea history, abortion, pathologic type, American Society for Reproductive Medicine (ASRM) stage, abnormal uterine bleeding, posterior fornix tender nodules, uterine enlargement, accessory area thickening, and delivery history (all P<0.05). Multivariate analysis confirmed that abortion (OR=1.31), ASRM stage ≥III (OR=1.03), abnormal uterine bleeding (OR=1.72), and posterior fornix tender nodules (OR=1.34) were independent predictors (all P<0.05). The nomogram (Logit (P)=-3.30+1.31X

conclusionPreoperative pathologic features are significant predictors of recurrence after laparoscopic surgery for EMs. Monitoring these markers can help clinicians identify high-risk patients and provide more targeted treatment.

Indexed as

Endometriosislaparoscopic surgeryline drawing modelrecurrencerisk factors

Identifiers

PMID40535644
PMCPMC12170414

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