Evidence map›Paper›PMID 40535633›Full record

ArticleAmerican journal of translational research2025

Clinical efficacy and safety analysis of ultrasound-guided radiofrequency ablation for varicose veins of lower extremities.

Ni Zhang, Haifeng Zhou, Yijiang Chen, Conghua Ding, Song Jiang

Abstract read
In one paragraph

Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ni ZhangDepartment of General Surgery, Hangzhou Fuyang Hospital of Traditional Chinese Medicine Hanghzou 311400, Zhejiang, China.
Haifeng ZhouDepartment of Statistics and Epidemiology, Hangzhou Fuyang Hospital of Traditional Chinese Medicine Hanghzou 311400, Zhejiang, China.
Yijiang ChenDepartment of General Surgery, Hangzhou Fuyang Hospital of Traditional Chinese Medicine Hanghzou 311400, Zhejiang, China.
Conghua DingMedical Imaging Division, Hangzhou Fuyang Hospital of Traditional Chinese Medicine Hanghzou 311400, Zhejiang, China.
Song JiangDepartment of Cerebral Vascular Surgery, Hangzhou Fuyang Hospital of Traditional Chinese Medicine Hanghzou 311400, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the efficacy of ultrasound-guided radiofrequency ablation (RFA) and high ligation and stripping (HL/S) for lower extremity varicose veins (VV).

methodsClinical data from 160 VV patients treated at Hangzhou Fuyang Hospital of Traditional Chinese Medicine between January 2023 and December 2024 were retrospectively analyzed. Patients were assigned to either the RFA group (n = 82, ultrasound-guided RFA) or the HL/S group (n = 78, HL/S) based on the treatment modality. Operative time, intraoperative blood loss, length of stay (LOS), Visual Analogue Scale (VAS) scores, levels of bradykinin (BK), substance P (SP), plasminogen activator inhibitor-1 (PAI-1), fibrinogen (Fib), dorsal foot vein pressure, complication rates, and 1-month follow-up outcomes including 36-Item Short Form Survey (SF-36) scores and venous clinical severity scores (VCSS) were compared between the two groups.

resultsThe RFA group demonstrated shorter operative time, less blood loss, and shorter LOS compared to the HL/S group (

conclusionUltrasound-guided RFA outperformed HL/S in reducing perioperative trauma, pain, dorsal foot vein pressure, and coagulation and inflammatory markers, while offering higher safety and improved short-term quality of life for VV patients.

Indexed as

clinical efficacyhigh ligation and strippingsafetyUltrasound-guided radiofrequency ablationvaricose veins of lower extremities

Identifiers

PMID40535633
PMCPMC12170403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.