Evidence map›Paper›PMID 40535552›Full record

ArticleFrontiers in malaria2024

Supplementing routine hospital surveillance of malaria to capture excess mortality and epidemiological trends: a five-year observational study.

Jean-Bertin Bukasa Kabuya, Caitlin Bond, Manuela Hauser, Jay Sikalima, Bruce Phiri, Dickson Phiri, Japhet Matoba, Jayme Hughes, Proscovia Miiye Banda, James Sichivula Lupiya and 4 more

Abstract read
In one paragraph

Article in Frontiers in malaria, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jean-Bertin Bukasa KabuyaClinical Sciences Department, Tropical Diseases Research Centre, Ndola, Zambia.
Caitlin BondDepartment of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Manuela HauserDepartment of Paediatrics, Cantonal Hospital Graubünden, Chur, Switzerland.
Jay SikalimaClinical Sciences Department, Tropical Diseases Research Centre, Ndola, Zambia.
Bruce PhiriOffice of Health Management Information Systems, Saint Paul's General Hospital, Nchelenge, Zambia.
Dickson PhiriOffice of Health Management Information Systems, Saint Paul's General Hospital, Nchelenge, Zambia.
Japhet MatobaMacha Research Trust, Choma, Zambia.
Jayme HughesDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Proscovia Miiye BandaClinical Laboratory, Saint Paul's General Hospital, Nchelenge, Zambia.
James Sichivula LupiyaClinical Sciences Department, Tropical Diseases Research Centre, Ndola, Zambia.
Gershom ChongweClinical Sciences Department, Tropical Diseases Research Centre, Ndola, Zambia.
Philip E ThumaMacha Research Trust, Choma, Zambia.
William J MossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.
Matthew M IppolitoJohns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States.

Funding

TransmissionU19AI089680 · NIAID · JOHNS HOPKINS UNIVERSITY · PI WILLIAM J MOSS · 2010 to 2026
$25.6M
Clinical Pharmacology of Malaria Control and Elimination: Pharmacodynamics ofArtemisinin-based Combination Agents and their Barriers to Drug ResistanceK23AI139343 · NIAID · JOHNS HOPKINS UNIVERSITY · PI IPPOLITO, MATTHEW MICHAEL · 2020 to 2023
$773k
The Averting Readmissions for Malaria and Outpatient Reinfections (ARMOR) TrialR34AI165307 · NIAID · JOHNS HOPKINS UNIVERSITY · PI IPPOLITO, MATTHEW MICHAEL · 2022 to 2022
$246k
NIAID NIH HHS K23 AI139343NIAID NIH HHS R34 AI165307NIAID NIH HHS U19 AI089680
6 · The paper itself

Abstract

Introduction: Malaria surveillance in Africa is conducted largely through health facility-based health management information systems (HMIS) which provide aggregated data to malaria control programs. Supplementation of HMIS surveillance with other routinely collected hospital data can provide vital statistics on malaria control in regions of high burden. Methods: To assess the utility of supplementing HMIS data, we implemented a pilot program of enhanced malaria surveillance in a district hospital in northern Zambia over a five-year period. Data were tabulated from existing nursing records, central pharmacy inventories, laboratory logbooks, and ward registers and cross-referenced with routinely collected HMIS data. Results: The additional data collections captured excess malaria deaths resulting from pharmacy and blood bank stockouts (10.3 excess deaths/year) and revealed small but significant changes over time in the age distribution of patients that likely reflect underlying shifts in the local epidemiology due to malaria control programming or other factors (median age from 1.9 to 2.4 months old, P=0.001). Discussion: Readily available data can supplement existing HMIS surveillance in high malaria burden areas to provide actionable information about the local epidemiology and impacts of control efforts. Excess malaria deaths due to health systems factors can be feasibly captured and tracked and fed back to national malaria control programs and the World Health Organization to present a fuller picture of malaria burden.

Indexed as

disease surveillancemalariaPlasmodium falciparumsevere malariaZambia

Identifiers

PMID40535552
PMCPMC12175441

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.