Evidence map›Paper›PMID 40535550›Full record

SynthesisFrontiers in surgery2025

Pituitary apoplexy: surgical or conservative? A meta-analytical insight.

Kailai Xia, Jihong Peng, Yunhao Zhou, Xiaoqing Liu, Hongyu Chen, Haiyang Xu, Shuangji Wang, Aini Deng, Hua Tang, Jinyang Hu

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kailai Xia *Department of Neurosurgery, The First College of Clinical Medical Science, Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.
Jihong Peng *College of Basic Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Yunhao Zhou *College of Basic Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Xiaoqing LiuDepartment of Anesthesiology, The First College of Clinical Medical Science, Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.
Hongyu ChenDepartment of Anesthesiology, The First College of Clinical Medical Science, Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.
Haiyang XuCollege of Basic Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Shuangji WangCollege of Basic Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Aini DengCollege of Basic Medical Sciences, China Three Gorges University, Yichang, Hubei, China.
Hua TangDepartment of Neurosurgery, The First College of Clinical Medical Science, Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.
Jinyang HuDepartment of Neurosurgery, The First College of Clinical Medical Science, Three Gorges University & Yichang Central People's Hospital, Yichang, Hubei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The challenge in treating pituitary apoplexy lies in choosing between conservative management and surgical intervention, with a current lack of high-level medical evidence to guide the selection of treatment options. This study compares the recovery rates of typical clinical manifestations following surgical and conservative treatments, aiming to provide evidence-based medical support for clinical treatment decisions. Methods: Relevant literature published between 1991 and 2024 was searched using PubMed, Embase, Cochrane Libraries, and CNKI. After a rigorous screening process to apply the inclusion and exclusion criteria, the primary clinical observation indicators were carefully extracted. The recovery rates of the main clinical observation indicators were evaluated using Reman v5.3. A fixed-effects model was employed to determine the merged odds ratio (OR) values, utilizing the Mantel-Haenszel estimation method. Publication bias was assessed using a funnel plot. Heterogeneity between studies was analyzed with the Cochran Q (Chi-square) test and I² statistics. Results: The meta-analysis results indicated that surgical treatment significantly improved recovery from ocular muscle paralysis compared to conservative treatment (OR: 0.31; 95% CI 0.10-0.92; Conclusion: Our research findings suggest that patients with pituitary apoplexy presenting with ocular palsy may benefit more from surgical treatment.

Indexed as

conservative treatmentmeta-analysispituitary apoplexysurgical treatmentsystematic review

Identifiers

PMID40535550
PMCPMC12174462

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.