Evidence map›Paper›PMID 40535497›Full record

ArticleWorld journal of transplantation2025

Ten years of a pediatric living donor liver transplantation program in Brazil.

Marco Aurélio Farina Junior, Melina Utz-Melere, Carolina Soares da Silva, Luiza Salgado Nader, Cristine Suzana Trein, Angelica Maria Lucchese, Mayara Machry, Rodrigo Mariano, Cristina Targa Ferreira, Antônio Nocchi Kalil and 1 more

Abstract read
In one paragraph

Article in World journal of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marco Aurélio Farina JuniorDepartment of Hepatology and Liver Transplantation, Santa Casa de Porto Alegre, Porto Alegre 90050-170, Brazil.
Melina Utz-MelereDepartment of Hepatology and Liver Transplantation, Santa Casa de Porto Alegre, Porto Alegre 90050-170, Brazil.
Carolina Soares da SilvaDepartment of Hepatology and Liver Transplantation, Santa Casa de Porto Alegre, Porto Alegre 90050-170, Brazil.
Luiza Salgado NaderDepartment of Hepatology and Liver Transplantation, Santa Casa de Porto Alegre, Porto Alegre 90050-170, Brazil.
Cristine Suzana TreinDepartment of Hepatology and Liver Transplantation, Santa Casa de Porto Alegre, Porto Alegre 90050-170, Brazil.
Angelica Maria LuccheseDepartment of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90020-090, Brazil.
Mayara MachryDepartment of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90020-090, Brazil.
Rodrigo MarianoDepartment of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90020-090, Brazil.
Cristina Targa FerreiraDepartment of Hepatology and Liver Transplantation, Santa Casa de Porto Alegre, Porto Alegre 90050-170, Brazil.
Antônio Nocchi KalilDepartment of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90020-090, Brazil.
Flávia Heinz FeierDepartment of Hepato-Biliary-Pancreatic Surgery and Liver Transplantation, Irmandade Santa Casa de Misericórdia de Porto Alegre, Porto Alegre 90020-090, Brazil. flavia.feier@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPediatric living-donor liver transplantation is considered a safe alternative for the treatment of children with end-stage liver disease. Experienced tertiary centers and specialized medical staff are necessary to ensure compatible long-term survival rates and quality-of-life for these children.

aimTo report the results and the 10-year learning curve of a pediatric living-donor liver transplantation program.

methodsWe conducted a retrospective cohort study of pediatric recipients from 2013 to 2023. Post-transplant outcomes and patient survival rates were compared between two 5-year periods of the program.

resultsA total of 25 and 48 patients underwent transplantation in the first (2013-2017) and second period (2018-2023), respectively. Portal vein and hepatic artery thrombosis occurred in 11 (15.1%) and seven (9.6%) patients, respectively. Biliary complications were observed in 39 of 73 patients (53.4%). A lower warm ischemia time was observed in the second period compared to the first (32.6 ± 8.6 minutes

conclusionThe reported indications and outcomes align with the current literature. Our findings provide crucial evidence regarding the feasibility of establishing a living donor program with consistent results over time.

Indexed as

End-stage liver diseaseLiver transplantLiving donorPediatric hepatologySurvival rate

Identifiers

PMID40535497
PMCPMC11886308

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.