Evidence map›Paper›PMID 40535479›Full record

ArticleWorld journal of transplantation2025

Effect of frailty as measured by functional impairment on long-term outcomes in liver transplantation in the United States.

Julius Balogh, Talha Mubashir, Yuan Li, Biai D Digbeu, Nikita Hegde, Fatemeh Movaghari Pour, Mohsen Rezapour, Hong-Yin Lai, Kelly West, Rabail A Chaudhry and 2 more

Abstract read
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In one paragraph

Article in World journal of transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Julius BaloghDepartment of CV Anesthesia, CHI St. Vincent Infirmary, Little Rock, AR 72205, United States.
Talha MubashirDepartment of CV Anesthesia, CHI St. Vincent Infirmary, Little Rock, AR 72205, United States.
Yuan LiDepartment of Biostatistics and Data Science, The University of Texas Health Center at Houston School of Public Health, Houston, TX 77030, United States.
Biai D DigbeuDepartment of Biostatistics and Data Science, The University of Texas Health Center at Houston School of Public Health, Houston, TX 77030, United States.
Nikita HegdeDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA 98195, United States.
Fatemeh Movaghari PourDepartment of Comprehensive Dentistry, UT Health San Antonio School of Dentistry, San Antonio, TX 78229, United States.
Mohsen RezapourVertex Pharmaceuticals, Boston, MA 02210, United States.
Hong-Yin LaiDepartment of Biostatistics and Data Science, The University of Texas Health Center at Houston School of Public Health, Houston, TX 77030, United States.
Kelly WestDepartment of Anesthesiology, Critical Care and Pain Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, United States.
Rabail A ChaudhryDepartment of Anesthesiology and Pain Medicine, University of Arizona College of Medicine-Tucson, Tucson, AZ 85724, United States.
George W WilliamsDepartment of Anesthesiology, Critical Care and Pain Medicine, The University of Texas Health Science Center at Houston McGovern Medical School, Houston, TX 77030, United States.
Vahed MaroufyDepartment of Biostatistics and Data Science, The University of Texas Health Center at Houston School of Public Health, Houston, TX 77030, United States. vahed.maroufy@uth.tmc.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients with chronic liver disease or hepatic dysfunction with sarcopenia, there is an increased risk of frailty as measured by functional impairment, making frailty a vital predictor of post-transplant mortality.

aimTo investigate the effects of frailty on mortality after liver transplantation.

methodsA retrospective review of post-transplant outcomes in liver transplant recipients assessed frailty using Karnofsky Performance Score. Data from the Scientific Registry of Transplant Recipients database for 37427 liver transplant recipients was used.

resultsOf 82.7% frail patients, 42.7% were severely frail and 40% were moderately frail (

conclusionRecipient frailty is associated with increased mortality at 12 months following liver transplantation, and liver transplants from donors with DCD are associated with increased frailty of the liver transplant recipient.

Indexed as

Alcohol-associated liver diseaseInsulin resistanceLiver transplantationNon-alcoholic steatohepatitisNon-alcoholic steatotic liver diseaseOxidative stress

Identifiers

PMID40535479
PMCPMC11886294

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.