Evidence map›Paper›PMID 40535416›Full record

ArticleCureus2025

Cytomegalovirus (CMV) Infection in Pregnancy Resulting in Neonatal Mortality Due to Congenital CMV: A Case Report.

Saima Faraz, Umniyah Abu-Nayla, Fadi Mirza, Nighat Aftab, Sofia A Malik

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saima FarazObstetrics and Gynecology, Latifa Women and Children Hospital, Dubai, ARE.
Umniyah Abu-NaylaObstetrics and Gynecology, Dubai Academic Health Corporation, Dubai, ARE.
Fadi MirzaObstetrics and Gynecology, Latifa Women and Children Hospital, Dubai, ARE.
Nighat AftabObstetrics and Gynecology, Latifa Women and Children Hospital, Dubai, ARE.
Sofia A MalikObstetrics and Gynecology, Latifa Women and Children Hospital, Dubai, ARE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital cytomegalovirus (cCMV) infection is a major cause of neonatal morbidity that can be easily overlooked, as only a few cases are symptomatic, leading to severe complications such as hearing loss, developmental delays, and brain damage. It is one of the most common congenital infections. A 37-year-old woman with a high-risk pregnancy, including preeclampsia and type 2 diabetes, presented at 30+2 weeks gestation with abdominal pain and reduced fetal movements. Ultrasound revealed intrauterine growth restriction (IUGR) and abnormal Doppler findings, prompting an emergency cesarean section. The newborn, weighing 1100g, showed signs of CMV infection, including jaundice and hepatosplenomegaly, which was confirmed by polymerase chain reaction (PCR) testing. Despite antiviral treatment, the infant's condition deteriorated with progressive neurological issues, such as intracranial hemorrhage and hydrocephalus, ultimately leading to death on day 39. This case highlights the severe consequences of undiagnosed CMV infection in high-risk pregnancies. It emphasizes the importance of early intervention and routine screening for maternal CMV infection in such cases.

Indexed as

congenital cytomegalovirus (ccmv)estimated fetal weight (efw)intrauterine growth restriction (iugr)pcr testingpreterm premature rupture of membranes (pprom)

Identifiers

PMID40535416
PMCPMC12176314

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.