ArticleCureus2025
Fighting the Fracture Cascade: Early and Repeated Balloon Kyphoplasty as a Bridge Until the Effects of Osteoporosis Treatment Become Apparent in a Super-Aged Patient.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Unilateral extrapedicular versus unilateral and bilateral transpedicular approaches in percutaneous vertebral augmentation for osteoporotic vertebral compression fractures: A meta-analysis.Joint diseases and related surgery · 2026Pooled it
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoporotic vertebral compression fractures are common in the elderly and frequently lead to pain, spinal deformity, and decreased activities of daily living (ADL). While balloon kyphoplasty (BKP) is known to provide rapid pain relief and improve mobility, it does not prevent the occurrence of subsequent adjacent vertebral fractures, especially before the therapeutic effects of pharmacologic osteoporosis treatments such as teriparatide become apparent. We report the case of an 87-year-old super-aged female patient who experienced a cascade of five adjacent vertebral fractures within four months. After conservative treatment failed, she underwent BKP for L1 and L4, resulting in immediate pain relief. However, new fractures subsequently occurred at Th12, L2, and L3, each requiring further BKP. Early surgical intervention after each fracture successfully restored mobility and preserved independence in ADL. Over a five-year follow-up period, no new fractures were observed, and spinal alignment was maintained. This case highlights the utility of early and repeated BKP as a bridging strategy until the effects of osteoporosis treatment take hold. Timely, minimally invasive interventions can prevent deterioration of spinal alignment and preserve quality of life in super-aged patients with severe osteoporosis.
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Registered trials
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