ReviewJournal of inflammation research2025
Role of Macrophage Polarization in Chronic Rhinosinusitis Based on the Yin-Yang Theory: A Review.
Review in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Exosomes-loaded with traditional Chinese medicine constituents: a novel therapeutic avenue for aplastic anemia.Chinese medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Chronic rhinosinusitis (CRS) is a prevalent otolaryngologic condition that markedly impacts patients' quality of life; however its pathogenesis is intricate and the clinical efficacy of known treatments remains limited. Methods: In recent years, there has been a growing focus on the role of immune function in the pathogenesis of CRS. Recent studies have revealed a correlation between macrophage polarization and CRS development. Macrophage polarization denotes distinct phenotypes of macrophages in diverse microenvironments, with the M1 and M2 phenotypes sharing similarities with the Yin-Yang concept of traditional Chinese medicine, encompassing mutual support and utilization, a balance between growth and elimination, and self-healing and equilibrium. Results: This study briefly reviews the latest research on traditional Chinese medicine compound prescriptions and the regulation of macrophage polarization by traditional Chinese medicine monomers, aligned with the main treatment principles of CRS, with the aim of offering novel directions and strategies for the clinical management of this condition. Conclusion: This study investigated the role of macrophage polarization in CRS from the perspective of the Yin-Yang Theory of traditional Chinese medicine.
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