Evidence map›Paper›PMID 40535223›Full record

ReviewIndian journal of thoracic and cardiovascular surgery2025

Surgically implanted temporary ventricular assist pump - "Impella 5.5".

Akshay Chauhan, Mikiko Senzai, Sriram Vijayapuri, Hiromu Kehara, Roh Yanagida, Kewal Krishan, Yoshiya Toyoda

Abstract readReview
In one paragraph

Review in Indian journal of thoracic and cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Akshay ChauhanDepartment of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.
Mikiko SenzaiDepartment of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.
Sriram VijayapuriDepartment of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.
Hiromu KeharaDepartment of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.
Roh YanagidaDepartment of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.
Kewal KrishanDepartment of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.
Yoshiya ToyodaDepartment of Cardiovascular Surgery, Lewis Katz School of Medicine, Temple University, Philadelphia, PA 19004 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Impella 5.5 (Abiomed, Danvers, MA, USA) is an advanced left ventricular assist device that provides short-term cardiac support for patients with severe heart failure and cardiogenic shock. Its compact size and catheter-based design facilitate relatively straightforward insertion, offering mechanical support to the left ventricle without significantly increasing afterload-two key advantages. A substantial body of clinical trials and real-world evidence have confirmed its efficacy in enhancing cardiac output and organ perfusion. Notably, its short-term support has been associated with improved patient outcomes in cases of cardiogenic shock. However, the use of Impella is not without risks, including bleeding events, peripheral vascular complications, and hemolysis, underscoring the importance of appropriate patient selection, surgical planning, and meticulous post-insertion management. Future research should focus on long-term outcomes, cost-effectiveness, and continued advancements in technology. This review provides a comprehensive analysis of the Impella device, including its design, clinical applications, surgical strategies, benefits, and indications, as well as the challenges associated with its use. It reassesses its role considering the most recent evidence.

Indexed as

Heart failureImpella 5.5Microaxial pump

Identifiers

PMID40535223
PMCPMC12170487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.