ArticleFrontiers in oncology2025
Validating a T1-weighted cine MRI for a 1.5T MR-Linac with temporal resolution appropriate for respiratory motion.
Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.
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Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: High temporal resolution cine magnetic resonance imaging (MRI) for the 1.5T Elekta Unity MR-Linac system currently relies on a balanced contrast sequence for motion monitoring (MM) and tumor tracking. Despite its high signal-to-noise ratio (SNR), a balanced contrast sequence does not always provide the ideal contrast for tumor imaging in all situations. Thus, the investigation of other contrast high temporal resolution cine MRI sequences is needed. Methods: Experiments were conducted to validate the T1-weighting and SNR on a cine MRI sequence with a frame rate of 4 frames-per-second (fps) and sufficient image quality. A ModusQA Quasar MRI4D motion phantom and Alzheimer's Disease Neuroimaging Initiative (ADNI) phantom were used to confirm adequate motion tracking, contrast-to-noise ratio (CNR), SNR, and T1 weighting of the new cine MRI sequence. Target tracking success using Elekta's Comprehensive Motion Management (CMM) algorithm was assessed on Results: The T1-weighted cine MRI sequence exhibited consistent CNR, SNR and T1-weighting over the duration of the scan while maintaining the ability to capture target motion within 1 mm at 4 fps. Conclusion: The proposed T1-weighted cine MRI sequence can produce quality T1-weighted images capable of tracking tumor motion over time. This demonstrates the sequence's potential in motion monitoring tasks as an alternative to the bTFE sequence when necessary.
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