Evidence map›Paper›PMID 40535130›Full record

ReviewFrontiers in oncology2025

The role of MYEOV gene: a review and future directions.

Yidan Xi, Xuefei Liu, Yanan Ge, Mingzhe Jiang, Dong Zhao, Ershu Zhao, Fei Cai, Xinlong Wang, Jiatong Li, Tingting Li and 1 more

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yidan Xi *Department of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Xuefei LiuDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Yanan Ge *Department of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Mingzhe JiangDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Dong ZhaoDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Ershu ZhaoDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Fei CaiDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Xinlong WangDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Jiatong LiDepartment of Periodontics, Stomatological Hospital, School of Stomatology, Southern Medical University, Guangzhou, China.
Tingting LiDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.
Zhendong ZhengDepartment of Oncology, General Hospital of Northern Theater Command, Shenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overexpressed gene MYEOV in multiple myeloma, as an oncogene, has been widely recognized for its high expression levels in various malignant tumors. MYEOV plays a significant role in multiple malignancies, particularly in diseases such as multiple myeloma, breast cancer, lung cancer, pancreatic cancer, and esophageal cancer. The presence of the open reading frame of MYEOV in humans and other primates suggests its potential protein-coding capacity, although direct evidence of functional MYEOV protein is currently lacking. The role of MYEOV in various tumors is not limited to its direct effects as an oncogene; it also includes its complex role in tumor cell signaling pathways and its ability to participate in miRNA regulatory networks as a competing endogenous RNA (ceRNA). Studies have shown that MYEOV may affect the expression of cancer-related genes through enhancer activity. This article aims to provide a comprehensive review of the role of MYEOV, its involvement in signaling pathways in tumor cells, and the latest advancements in MYEOV-targeted therapies.

Indexed as

biomarker therapyMYEOVsignaling pathwaytargettumor

Identifiers

PMID40535130
PMCPMC12175006

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.