Evidence map›Paper›PMID 40535121›Full record

ReviewFrontiers in oncology2025

Current status, hotspots and frontiers of ion channel-related research in glioblastoma: a bibliometric analysis from 2005 to 2024.

Zefeng He, Jing Liu, Qianxu Jin, Shangkun Ren, Liang Liu, Yingzi Liu

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zefeng HeNeurosurgery Department, The 4th Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Jing LiuNeurosurgery Department, The 4th Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Qianxu JinNeurosurgery Department, The 4th Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Shangkun RenNeurosurgery Department, The 4th Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Liang LiuNeurosurgery Department, The 4th Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.
Yingzi LiuNeurosurgery Department, The 4th Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma is the most common primary tumor of the central nervous system, with glioblastoma being its predominant pathological type. In recent years, research has demonstrated that ion channels are intricately linked with numerous biological processes in tumor cells, including apoptosis and migration, among others. This study employs bibliometric analysis to systematically examine and synthesize the knowledge structure and research focal points in the field of glioblastoma ion channels. Publications related to ion channels in glioblastoma, published between January 1, 2005 and December 31, 2024, were retrieved from the Web of Science Core Collection (WoSCC). The dataset comprises 764 articles and 234 reviews. Utilize VOSviewer, CiteSpace, Bibliometrix, and Excel to conduct an in-depth analysis and visualization of scholarly contributions based on country, institution, journal, and author. Additionally, examine highly cited publications, references, and keywords. From 2005 to 2024, the number of publications in this field has shown a consistent annual increase. The University of Alabama and Cancer are among the leading institutions and journals. Sontheimer Harald, from the United States, is the most prolific author in this field. The analysis of highly cited publications and co-cited references indicates that the research background and foundation focus on elucidating the mechanisms by which ion channels influence the onset and progression of glioblastoma. Keyword analysis indicated that "tumor microenvironment" (burst strength: 4. 67), "Ca

Indexed as

apoptosisbibliometric analysisglioblastomaion channelnanoparticlesingle-cell spatial transcriptomicstumor microenvironment

Identifiers

PMID40535121
PMCPMC12174454

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.