Evidence map›Paper›PMID 40534882›Full record

ArticleFrontiers in immunology2025

Cytokine secretion patterns distinguish herpes simplex virus type 2 meningitis from herpes simplex virus type 2 genital herpes.

Moa Bjerhem, Alexandra Svensson, Marie Studahl, Petra Tunbäck, Eva-Marie Boman, Kenny Brandström, Christine Lingblom, Azadeh Reyahi, Karolina Thörn, Kristina Eriksson

Abstract read
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In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Moa BjerhemDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Alexandra SvenssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Marie StudahlDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Petra TunbäckDepartment of Dermatovenerology, Sahlgrenska University Hospital, Gothenburg, Sweden.
Eva-Marie BomanDepartment of Infectious Diseases, Södra Älvsborg Hospital, Borås, Sweden.
Kenny BrandströmDepartment of Infectious Diseases, Skaraborg Hospital, Skövde, Sweden.
Christine LingblomDepartment of Infectious Diseases, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden.
Azadeh ReyahiDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Karolina ThörnDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Kristina ErikssonDepartment of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to identify immune factors that distinguish patients with herpes simplex virus type 2 (HSV-2) meningitis from patients with HSV-2 genital herpes by analyzing demographic data,

Indexed as

CytokinesHerpes GenitalisHerpesvirus 2, HumanMeningitis, ViralAdultAgedAntibodies, ViralDiagnosis, DifferentialFemaleHumansLeukocytes, MononuclearMaleMiddle AgedYoung AdultAntibodies, ViralCytokinescytokinesgenital herpesHSV-2immune profilemeningitismultivariate analysis

Identifiers

PMID40534882
PMCPMC12174149

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.