Evidence map›Paper›PMID 40534857›Full record

ArticleFrontiers in immunology2025

T cell-mediated immune surveillance conferred by latent Epstein-Barr virus genes suppresses a broad spectrum of tumor formation through NKG2D-NKG2DL interactions.

Yuqi Jin, Yun Guo, Yohei Kawano, Megumi Sasatani, Shun Ohki, Keita Yamane, Yusei Ota, Yumi Tamura, Yusuke Sotomaru, Yoshihiro Baba and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yuqi JinDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yun GuoDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yohei KawanoDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Megumi SasataniDepartment of Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Shun OhkiDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Keita YamaneDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yusei OtaDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yumi TamuraDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yusuke SotomaruNatural Science Center for Basic Research and Development, Hiroshima University, Hiroshima, Japan.
Yoshihiro BabaDivision of Immunology and Genome Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Tomoharu YasudaDepartment of Immunology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV)-infected B cells effectively induce T cell-mediated immune surveillance that suppresses the proliferation of EBV

Indexed as

Epstein-Barr Virus InfectionsHerpesvirus 4, HumanImmunologic SurveillanceNK Cell Lectin-Like Receptor Subfamily KViral Matrix ProteinsAnimalsB-LymphocytesCD8-Positive T-LymphocytesHumansMiceMice, Inbred C57BLEBV-associated membrane antigen, Epstein-Barr virusKlrk1 protein, mouseNK Cell Lectin-Like Receptor Subfamily KViral Matrix ProteinsApcMinEpstein-Barr virusimmune surveillanceLMP1LMP2ANKG2Dradiation-induced tumorT-ALL

Identifiers

PMID40534857
PMCPMC12174148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.