Evidence map›Paper›PMID 40534778›Full record

ArticleFrontiers in veterinary science2025

Epidemiological investigation, related factors, spatial-temporal cluster analysis of pseudorabies virus seroprevalence in Guangdong Province of China.

Mengpo Zhao, Jing Chen, Shengjun Luo, Pian Zhang, Jinliang Chen, Chenglong Sun, Zhaowen Ren, Yanju Huang, Xiaoxiao Zhang, Hua Xiang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mengpo Zhao *College of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Jing Chen *Guangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Shengjun Luo *Guangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Pian ZhangGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Jinliang ChenGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Chenglong SunDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Harry Hines Boulevard, Dallas, TX, United States.
Zhaowen RenGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Yanju HuangCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xiaoxiao ZhangGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Hua XiangGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Yuan HuangGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Gang WangGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.
Zi-Guo YuanCollege of Veterinary Medicine, South China Agricultural University, Guangzhou, China.
Xiaohu WangGuangdong Provincial Key Laboratory of Livestock Disease Prevention, Guangdong Provincial Observation and Research Station for Animal Disease, Institute of Animal Health, Guangdong Academy of Agricultural Sciences, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Pseudorabies (PR) is an important zoonotic viral disease that infects a wide range of animals, including humans. In recent years, the prevalence of pseudorabies virus (PRV) has caused great economic losses to the Chinese pig industry. Methods: In this study, 40,050 serum samples were collected from 348 pig farms in 18 districts of Guangdong Province, China, between 2017 and 2022 to investigate the seroprevalence of wild-type PRV in pigs. Results: The results of the enzyme-linked immunosorbent assay (ELISA) showed that seropositivity for PRV gE antibodies was 25.28% (95% CI, 24.86% to 25.71%) at the pig level. However, the seropositivity of PRV gE antibodies reached 67.44 % (95% CI, 62.14% to 71.96%) at the farm level. To identify potential factors associated with the positive rate of PRV gE antibodies, logistic regression analysis was performed, and the results showed that the seropositivity rate of PRV gE was related to factors such as geographic distribution and season. To find areas with higher PR prevalence in Guangdong Province, China, we analyzed the data using SaTScan 10.2.5 software and identified five spatiotemporal clusters of higher PRV gE antibody positivity in Guangdong Province, China, with the highest prevalence from April to June 2018. Conclusion: Our study revealed seroprevalence, associated influencing factors, and spatiotemporal clustering characteristics of PRV gE antibody positivity in Guangdong Province, China, in recent years. This provides new scientific data for the development of policies related to the prevention and control of wild-type pseudorabies epidemics in Guangdong Province, China.

Indexed as

epidemiological investigationGuangdong province trainable epidemiological investigationpseudorabies virusrelated factorsseroprevalencespatial–temporal clustering

Identifiers

PMID40534778
PMCPMC12174391

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.