Evidence map›Paper›PMID 40534612›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Mini review: Apple improvement, traditional approaches, biotechnology options, and regulatory considerations.

Amy L Klocko

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Amy L KlockoDepartment of Biology, University of Colorado Colorado Springs, Colorado Springs, CO, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apples are a popular and globally important crop. The fruits are eaten fresh, pressed for juice, fermented as cider, processed into sauce, dried, and more. There are thousands of different cultivars, a small subset of which are grown on a commercial scale. Genetic analysis has shown that, as a group, domestic apples have a complicated genetic background, with contributions from multiple wild species. By contrast, most of the highly produced commercialized modern cultivars share a narrow range of genetic diversity. However, as apples are outcrossing, propagated vegetatively, and long-lived, wild and heirloom varieties can be maintained and are valuable sources of genetic diversity for desirable traits. Apples are also amenable to genetic transformation, and work in this area has resulted in improved resistance to diseases and a commercialized non-browning variety, the Arctic™ Apple. Traditional breeding, breeding guided by modern genetic knowledge, and biotechnology all contribute to the overall process of apple cultivar development and represent an important example of how many approaches can be used in crop improvement. As global biosafety regulations continue to develop and change, countries will be tasked with developing guidelines for both the creation and import of apple trees and apple products.

Indexed as

appleapple scabbiotechnologybreedingfire blightgermplastGMO

Identifiers

PMID40534612
PMCPMC12175005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.