ReviewEuropean journal of immunology2025
Narrowing Down Key Players in Autoimmunity via Single-Cell Multiomics.
Review in European journal of immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Antibody-drug conjugate engineering: from design to efficacy and safety.Signal transduction and targeted therapy · 2026Review
- Multi-omics-driven precision medicine.iMeta · 2026Review
- Structural Modulation and Binding of HLA-DQ8 by Cysteine-to-Serine Mutated Insulin Peptide: Insights from Molecular Dynamics Simulations.International journal of molecular sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Autoimmune diseases encompass a range of conditions in which our own immune system reacts against molecules encoded by our own genome. This phenomenon is mediated by the action of antigen receptors expressed by T and B cells. Identifying the molecular events that trigger these responses as well as the effector cells that underlie them is at the heart of autoimmunity research. In this review, we discuss how single-cell multiomics techniques applied to healthy and patient tissues are shedding light on the mechanisms underpinning autoimmune conditions, specifically by identifying disease-associated cell states and cellular communication networks, including those linked to specific autoimmunity susceptibility genetic loci. Furthermore, we dive into the unprecedented resolution achieved in mapping autoreactive lymphocytes, a key component of autoimmune responses. We conclude with a perspective on key bottlenecks and promising future directions leveraging the latest advances in single-cell sequencing with orthogonal methods.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.