Evidence map›Paper›PMID 40534401›Full record

SynthesisAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2026

A systematic review of interventions for persons living with dementia: The Geriatric ED Guidelines 2.0.

Sangil Lee, Michelle Suh, Luna Ragsdale, Justine Seidenfeld, James D van Oppen, Lauren Lapointe-Shaw, Carolina Diniz Hooper, James Jaramillo, Annie B Wescott, Alexander X Lo and 7 more

Abstract readSystematic Review
In one paragraph

Synthesis in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. A systematic review of interventions for persons living with dementia: The Geriatric ED Guidelines 2.0.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Pooled it
  3. Article
  4. Disposition at Equipoise: A Qualitative Study of Emergency Physicians' Decision-Making About Hospitalizing People With Dementia.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Sangil LeeDepartment of Emergency Medicine, College of Medicine, University of Iowa Carver, Iowa City, Iowa, USA.
Michelle SuhSection of Emergency Medicine, University of Chicago, Chicago, Illinois, USA.
Luna RagsdaleEmergency Department, Durham Veterans Affairs Health Care System, Durham, North Carolina, USA.
Justine SeidenfeldEmergency Department, Durham Veterans Affairs Health Care System, Durham, North Carolina, USA.ORCID 0000-0001-6912-7315
James D van OppenCentre for Urgent and Emergency Care Research, University of Sheffield, Sheffield, UK.ORCID 0000-0002-2570-7112
Lauren Lapointe-ShawDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Carolina Diniz HooperDepartment of Emergency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
James JaramilloFrank H. Netter MD School of Medicine, Quinnipiac University, Hamden, Connecticut, USA.
Annie B WescottGalter Health Sciences Library & Learning Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Alexander X LoDepartment of Emergency Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Kaiho HirataDepartment of Emergency Medicine, International University of Health and Welfare Narita, Chiba, Japan.ORCID 0009-0006-4251-639X
Maura KennedyDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Lauren Cameron ComascoDepartment of Emergency Medicine, Corewell Health William Beaumont University Hospital, Royal Oak, Michigan, USA.
Christopher R CarpenterDepartment of Emergency Medicine, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0002-2603-7157
Teresita M HoganSection of Emergency Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA.
Shan W LiuDepartment of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-5602-3717
Geriatric ED Guidelines Dementia Writing Group

Funding

John A. Hartford FoundationWest health
6 · The paper itself

Abstract

backgroundThe increasing prevalence of dementia poses significant challenges for emergency department (ED) care, as persons living with dementia (PLWD) more frequently experience adverse outcomes such as delirium, prolonged stays, and higher mortality rates. Despite advancements in care strategies, a critical gap remains in understanding how ED interventions impact outcomes in this vulnerable population. This systematic review aims to identify evidence-based ED care interventions tailored to PLWD to improve outcomes.

methodsA systematic review was conducted in Ovid MEDLINE, Cochrane Library (Wiley), Scopus (Elsevier), and ProQuest Dissertations & Theses Global through September 2024. The review protocol was registered on PROSPERO (CRD42024586555). Eligible studies included randomized controlled trials, observational studies, and quality improvement initiatives focused on ED interventions for PLWD. Data extraction and quality assessment were performed independently by two reviewers, with disagreements resolved through discussion. Outcomes included patient satisfaction, ED revisits, functional decline, and mortality.

resultsFrom 3305 screened studies, six met the inclusion criteria. Interventions included nonpharmacologic therapies (e.g., music and light therapy), specialized geriatric ED units, and assessment tools, such as for pain. Tailored interventions including geriatric emergency units and community paramedic care transitions were effective in reducing 30-day ED revisits and hospitalizations. However, heterogeneity in study designs and outcomes precluded meta-analysis. Risk of bias ranged from low to moderate.

conclusionThis review underscores the urgent need for standardized and evidence-based interventions in ED settings for PLWD. Approaches including multidisciplinary care models and nonpharmacologic therapies demonstrated potential for improving outcomes. Future research should prioritize consistent outcome measures, interdisciplinary collaboration, and person-centered care strategies to enhance the quality and equity of ED services for PLWD.

Indexed as

DementiaEmergency Service, HospitalGeriatricsPractice Guidelines as TopicAgedHumansAlzheimer's disease and related dementiadementiaemergency departmentinterventionpreventionsystematic review

Identifiers

PMID40534401
PMCPMC12834197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.