Evidence map›Paper›PMID 40534324›Full record

Observational studyActa anaesthesiologica Scandinavica2025

Laryngotracheal Pathologies and Symptoms Associated to Airway Management of Critically Ill COVID-19 Patients at One-Year Follow Up: An Observational Study.

Svenberg Lind Clara, Karlsson Agneta, Marsk Elin, Kåhlin Jessica, Von Beckerath Mathias, Mårtensson Johan, Wanecek Michael, Vlastos Andrea, Hynning Boel, Aspelund Liljequist Amalia and 2 more

Abstract readObservational Study
In one paragraph

Observational study in Acta anaesthesiologica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Svenberg Lind ClaraDepartment of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0003-4075-3253
Karlsson AgnetaDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Marsk ElinDepartment of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Kåhlin JessicaDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.ORCID 0000-0001-5266-5272
Von Beckerath MathiasDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Mårtensson JohanDepartment of Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Wanecek MichaelDepartment of Anaesthesia, St Görans Hospital, Stockholm, Sweden.
Vlastos AndreaDepartment of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Hynning BoelKarolinska Institutet, Stockholm, Sweden.
Aspelund Liljequist AmaliaKarolinska Institutet, Stockholm, Sweden.
Söderin LouiseKarolinska Institutet, Stockholm, Sweden.
Wales JeremyDepartment of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.

Funding

Stiftelsen Acta Oto-Laryngologica
6 · The paper itself

Abstract

backgroundThe European laryngological society predicted an increased incidence of laryngotracheal complications as a result of the COVID-19 pandemic. During the first pandemic wave in the Stockholm region, 31% of critically ill COVID-19 patients were tracheotomized by an open surgical (OST) or a percutaneous tracheotomy (PCT). The aim of this study was to investigate the incidence of visible laryngotracheal pathologies in tracheotomized and long-term intubated COVID-19 survivors ≥ 12 months after initial intubation, to examine whether these pathologies were symptomatic and to assess possible associated factors.

methodsStudy participants underwent laryngotracheoscopy under local anaesthesia, and tracheostomy skin and soft tissue scars were photo documented. Patient-reported outcome measures - the Voice Handicap Index-10 (VHI-10), the Eating Assessment Tool-10 (EAT-10) and the Dyspnea Index (DI), and demographics were retrospectively extracted from patient medical records.

resultsOf 73 included study participants (40 OST, 24 PCT and 9 long-term intubated), 58% had visible laryngotracheal pathologies. Tracheostomy tube size and the number of days with tracheostomy were associated with skin and soft tissue pathology and tracheal pathology (p < 0.05). The results of the VHI-10 and EAT-10 were congruent with both laryngeal and skin and soft tissue pathologies. Participants with the highest DI scores, indicating breathing difficulties, had both laryngeal and tracheal pathologies followed by tracheal pathology alone.

conclusionsA high incidence of visible laryngotracheal pathologies, two airway management-related factors, and symptom-pathology associations for VHI-10 and EAT-10 scores were found in a cohort of COVID-19 survivors ≥ 12 months after critical care.

Indexed as

Airway ManagementCOVID-19Laryngeal DiseasesLarynxTracheal DiseasesAdultAgedAged, 80 and overCritical IllnessFemaleFollow-Up StudiesHumansIntubation, IntratrachealLaryngoscopyMaleMiddle Aged

Identifiers

PMID40534324
PMCPMC12177439

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.