Evidence map›Paper›PMID 40534225›Full record

Observational studyEuropean journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery2025

Iatrogenic aortic dissection in minimally invasive cardiac surgery for atrioventricular valves and atrial structures†.

Sebastian Johannes Bauer, Yukiharu Sugimura, Friederike Irmgard Schoettler, Moritz Benjamin Immohr, Tomoyuki Suzuki, Arash Mehdiani, Hug Aubin, Artur Lichtenberg, Payam Akhyari

Abstract readObservational Study
In one paragraph

Observational study in European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Sebastian Johannes BauerDepartment of Cardiac Surgery, Medical Faculty and University Hospital, Heinrich-Heine-University, Dusseldorf, Germany.ORCID 0000-0003-3135-3952
Yukiharu SugimuraDepartment of Cardiac Surgery, Medical Faculty and University Hospital, Heinrich-Heine-University, Dusseldorf, Germany.ORCID 0000-0003-0217-7363
Friederike Irmgard SchoettlerDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, Essen, Germany.ORCID 0000-0002-4359-7666
Moritz Benjamin ImmohrDepartment of Cardiac Surgery, Medical Faculty and University Hospital, Heinrich-Heine-University, Dusseldorf, Germany.ORCID 0000-0003-1051-8105
Tomoyuki SuzukiDepartment of Thoracic and Cardiovascular Surgery, West German Heart and Vascular Center, University Hospital Essen, Essen, Germany.
Arash MehdianiDepartment of Cardiac Surgery, Medical Faculty and University Hospital, Heinrich-Heine-University, Dusseldorf, Germany.ORCID 0000-0002-5794-223X
Hug AubinDepartment of Cardiac Surgery, Medical Faculty and University Hospital, Heinrich-Heine-University, Dusseldorf, Germany.ORCID 0000-0001-9289-8927
Artur LichtenbergDepartment of Cardiac Surgery, Medical Faculty and University Hospital, Heinrich-Heine-University, Dusseldorf, Germany.ORCID 0000-0001-8580-6369
Payam AkhyariDepartment of Cardiac Surgery, Medical Faculty and University Hospital, Heinrich-Heine-University, Dusseldorf, Germany.ORCID 0000-0002-6452-8678

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn the last decades, minimally invasive cardiac surgery has emerged as an alternative approach to conventional median sternotomy. However, some reports state an increased risk of iatrogenic acute aortic dissection. Evidence remains limited regarding preoperative diagnostics for risk reduction and the appropriate adjustment of surgical procedures if acute aortic dissection is detected intraoperatively.

methodsIn this retrospective single-centre observational study, we analysed 1065 patients who underwent minimally invasive cardiac surgery via right anterolateral thoracotomy for atrioventricular valves and atrial structures with femoral cannulation for cardiopulmonary bypass from August 2009 to June 2021. Occurrence of iatrogenic acute aortic dissection was evaluated, along with patient profiles and the primary composite outcome of major adverse cardiovascular events (non-fatal stroke, myocardial infarction or cardiovascular death). An optimal perioperative strategy was subsequently described.

resultsIntraoperative iatrogenic acute aortic dissection was observed in 8 patients (0.75%). It was identified at the start of cardiopulmonary bypass in 4 patients (50.0%). All patients underwent conversion to full sternotomy; 7 patients underwent additional aortic surgery with circulatory arrest thereafter. In-hospital mortality was 37.5% (n = 3), including 1 intraoperative death. Non-fatal stroke was observed in 12.5% (n = 1). A preoperative computed tomography scan was missing in 3 patients with aortic calcification (n = 1) and hostile peripheral arteries (n = 2).

conclusionsIntraoperative aortic dissection in minimally invasive cardiac surgery remains a rare complication. Frequent major adverse cardiovascular events highlight the importance of preoperative imaging based procedure planning. Intraoperatively, early diagnosis with standardized monitoring and time- and location-specific surgical adaptations might increase safety and outcomes.

Indexed as

Aortic DissectionCardiac Surgical ProceduresHeart AtriaHeart ValvesIatrogenic DiseaseIntraoperative ComplicationsMinimally Invasive Surgical ProceduresAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesCardiopulmonary bypassExtracorporeal circulationIatrogenic aortic dissectionMinimally invasive cardiac surgery

Identifiers

PMID40534225
PMCPMC12199776

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.