Evidence map›Paper›PMID 40534170›Full record

ReviewPlant biotechnology journal2025

Exploring potential strategies for haploid induction based on double fertilization in plants.

Tengyu Li, Chenlei Wang, Jingwen Pan, Javaria Tabusam, Yan Li, Jinbo Yao, Wei Chen, Yazhong Wang, Wei Gao, Junkang Rong and 5 more

Abstract readReview
In one paragraph

Review in Plant biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. AutoSiQ: a curated haploidFrontiers in plant science · 2026
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tengyu Li *State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.ORCID https://orcid.org/0000-0002-4453-7411
Chenlei Wang *State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.
Jingwen Pan *State Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.
Javaria TabusamState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.
Yan LiState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.
Jinbo YaoState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.
Wei ChenState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.ORCID https://orcid.org/0000-0002-5852-585X
Yazhong WangDepartment of Chromosome Biology, Max Planck Institute for Plant Breeding Research, Cologne, Germany.
Wei GaoNational Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Henan University, Henan, China.ORCID https://orcid.org/0000-0002-1391-8334
Junkang RongThe Key Laboratory for Quality Improvement of Agricultural Products of Zhejiang Province, Zhejiang Agricultural and Forestry University, Hangzhou, China.
Zeeshan AhmadState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.ORCID https://orcid.org/0000-0001-5367-9318
Andreas HoubenDepartment of Breeding Research, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK) Gatersleben, Seeland, Germany.ORCID https://orcid.org/0000-0003-3419-239X
Shouhong ZhuState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.
Shuangxia JinNational Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, China.ORCID https://orcid.org/0000-0002-1495-9154
Yongshan ZhangState Key Laboratory of Cotton Bio-breeding and Integrated Utilization, Institute of Cotton Research, Chinese Academy of Agricultural Science, Anyang, China.

Funding

China Scholarship Council 202303250081National Engineering Research Center of Cotton Biology Breeding and Industrial Technology/Institute of Cotton Research of CAAS NERC010115Natural Science Foundation of Henan 242300421340
6 · The paper itself

Abstract

Haploid induction (HI), an indispensable procedure in doubled haploid breeding, has attracted increasing attention in crop genetic improvement due to its ability to rapidly fix desirable traits in a homozygous state, thereby shortening the breeding cycle. However, HI has only been successfully implemented in a limited number of crops, and its underlying mechanisms remain largely enigmatic. This review summarizes five potential HI routes based on previous findings and the key events during the process of double fertilization in flowering plants. Among these HI methods, we suggest that sperm DNA fragmentation and ectopic expression of embryogenesis activator, as straightforward avenues for discovering new HI-related genes. We also emphasize that the combination of genome editing techniques with HI is a promising strategy to accelerate crop improvement and doubled haploid breeding. We envision that the proposed directions can pave the way for improving and deepening our understanding of HI mechanisms.

Indexed as

Crops, AgriculturalHaploidyPlant BreedingPollinationFertilizationGene Editingdouble fertilizationectopic expressionhaploid inductionmembrane fusionsperm DNA fragmentationuniparental chromosome elimination

Identifiers

PMID40534170
PMCPMC12392945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.